While most cigarette smokers endorse a desire to quit smoking, only about 14% to 49% will
achieve abstinence after 6 months or more of treatment. A greater understanding of the …

While most cigarette smokers endorse a desire to quit smoking, only 14–49% will achieve
abstinence after 6 months or more of treatment. A greater understanding of the effects of …

Background: Cigarette smoking is the main cause of preventable death in developed
countries. While the direct positive behavioral reinforcing effect of nicotine has historically …

This chapter reviews studies that have applied magnetic resonance imaging (MRI) toward a
better understanding of the neurobiological correlates and consequences of cigarette …

Understanding nicotine's neurobiological and cognitive mechanisms may help explain both
its addictive properties and potential therapeutic applications. As such, functional MRI was …

Modern functional neuroimaging techniques allow nicotine and tobacco researchers to
investigate the neurobiological basis of addiction in humans. We introduce the methods and …

Significant advances in human functional brain imaging offer new opportunities for direct
observation of the effects of nicotine, novel nicotinic agonists and nicotinic antagonists on …

OBJECTIVE: The effects of acute nicotine administration and smoking on brain function were
investigated in two studies, with the primary goal of identifying neural systems that mediate …

The present paper proposes a model for the identification and the validation of brain
processes and mechanisms underlying smokers' cue reactivity. Smoking behaviour is …

OBJECTIVE: Nicotine is a highly addictive substance, and cigarette smoking is a major
cause of premature death among humans. Little is known about the neuropharmacology …