The skin is the outermost protective barrier of the human body. Its role is to protect against
different physical, chemical, biological and environmental stressors. The vast majority of …

Ultraviolet (UV) exposure to the skin causes photo-damage and acts as the primary
etiological agent in photo-carcinogenesis. UV-B exposure induces cellular damage and is …

The skin acts as both physical as well as an immunological barrier against hazardous
agents from the outside environment and protects the internal organs against damage. Skin …

Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …

Ultraviolet (UV) exposure and atmospheric pollution are both independently implicated in
skin diseases such as cancer and premature aging. UVA wavelengths, which penetrate in …

Autophagy is an essential cellular process that maintains balanced cell life. Restriction in
autophagy may induce degenerative changes in humans. Natural or pathological aging of …

Background Autophagy is known as an intracellular cleanup system necessary to maintain
homeostasis of the skin. Many studies have pointed out the relationship between aging and …

The incidence of melanoma and non-melanoma skin cancer (NMSC) has been steadily
increasing over the past decades (1). With millions of people affected worldwide, skin cancer …

Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …

Autophagy is a membrane traffic system that provides sustainable degradation of cellular
components for homeostasis, and is thus considered to promote health and longevity …