A versatile method for the construction of C (sp2)-linked cyclophane peptide macrocycles via
Pd-catalyzed picolinamide-directed intramolecular arylation of aryl and alkenyl C–H bonds …

A series of tunable pH-dependent BODIPY dyes were synthesized and further functionalized
in a Knoevenagel condensation reaction with various aldehydes. In this fashion …

One‐pot multiple peptide ligation is a key technology to improve the efficiency of chemical
protein synthesis. One‐pot repetitive peptide ligation requires a cycle of three steps: peptide …

Peptide–protein interactions are important mediators of cellular-signaling events.
Consensus binding motifs (also known as short linear motifs) within these contacts underpin …

Oxazole is an important pharmacophore and exists in the backbone of many bioactive
peptide natural products and peptidomimetics. Efficient methods for the synthesis and direct …

A series of asymmetrical benzo-fused BODIPY dyes were synthesized from the Sonogashira
coupling and nucleophilic substitution reactions on the 3-halogenated benzo-fused BODIPY …

The world of organic luminophores has been confined for a long time to fairly standard
biological labeling applications and to certain analytical tests. Recently, however, the field …

Late-stage peptide modification showcases a huge potential for the construction of peptide
libraries, and the investigation of structure–activity relationships. Herein we report a dimethyl …

Conspectus α-Amino acids (αAA) are one of the most useful chiral building blocks for
synthesis. There are numerous general strategies that have commonly been used for αAA …

Water-soluble BODIPY dyes have been readily obtained by introduction of phosphonate
fragments either on the boron for the green and yellow emitting dyes or on the side chain for …