[HTML][HTML] Metabolic effects of the intracellular regulation of thyroid hormone: old players, new concepts

AG Cicatiello, D Di Girolamo, M Dentice - Frontiers in endocrinology, 2018 - frontiersin.org
Thyroid hormones (THs) are key determinants of cellular metabolism and regulate a variety
of pathways that are involved in the metabolism of carbohydrates, lipids and proteins in …

Thyroid hormone signaling in energy homeostasis and energy metabolism

EA McAninch, AC Bianco - Annals of the New York Academy of …, 2014 - Wiley Online Library
The thyroid hormone (TH) plays a significant role in diverse processes related to growth,
development, differentiation, and metabolism. TH signaling modulates energy expenditure …

The role of thyroid hormone in metabolism and metabolic syndrome

PFS Teixeira, PB Dos Santos… - … in endocrinology and …, 2020 - journals.sagepub.com
Metabolic syndrome (MetS) and thyroid dysfunction are common in clinical practice. The
objectives of this review are to discuss some proposed mechanisms by which thyroid …

[HTML][HTML] Thyroid hormone regulation of metabolism

R Mullur, YY Liu, GA Brent - Physiological reviews, 2014 - journals.physiology.org
Thyroid hormone (TH) is required for normal development as well as regulating metabolism
in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially …

Thyroid hormone action in metabolic regulation

Y Song, X Yao, H Ying - Protein & cell, 2011 - Springer
Thyroid hormone plays pivotal roles in growth, differentiation, development and metabolic
homeostasis via thyroid hormone receptors (TRs) by controlling the expression of TR target …

Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences

B Gereben, A Zeöld, M Dentice, D Salvatore… - Cellular and Molecular …, 2008 - Springer
The thyroid hormone plays a fundamental role in the development, growth, and metabolic
homeostasis in all vertebrates by affecting the expression of different sets of genes. A group …

Metabolic effects of thyroid hormone derivatives

M Moreno, P de Lange, A Lombardi, E Silvestri… - Thyroid, 2008 - liebertpub.com
The processes and pathways mediating the intermediary metabolism of carbohydrates,
lipids, and proteins are all affected by thyroid hormones (THs) in almost all tissues. Particular …

Paradigms of dynamic control of thyroid hormone signaling

AC Bianco, A Dumitrescu, B Gereben… - Endocrine …, 2019 - academic.oup.com
Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …

Deiodinases and the metabolic code for thyroid hormone action

SC Russo, F Salas-Lucia, AC Bianco - Endocrinology, 2021 - academic.oup.com
Deiodinases modify the biological activity of thyroid hormone (TH) molecules, ie, they may
activate thyroxine (T4) to 3, 5, 3′-triiodothyronine (T3), or they may inactivate T3 to 3, 3 …

[PDF][PDF] Thyroid: biological actions of 'nonclassical'thyroid hormones

R Senese, F Cioffi, P de Lange, F Goglia, A Lanni - J Endocrinol, 2014 - researchgate.net
Thyroid hormones (THs) are produced by the thyroid gland and converted in peripheral
organs by deiodinases. THs regulate cell functions through two distinct mechanisms …