Quantitative proteomics to study carbapenem resistance in Acinetobacter baumannii

V Tiwari, M Tiwari - Frontiers in microbiology, 2014 - frontiersin.org
Acinetobacter baumannii is an opportunistic pathogen causing pneumonia, respiratory
infections and urinary tract infections. The prevalence of this lethal pathogen increases …

A systematic quantitative proteomic examination of multidrug resistance in Acinetobacter baumannii

S Chopra, K Ramkissoon, DC Anderson - Journal of proteomics, 2013 - Elsevier
Multidrug-resistant Acinetobacter baumannii strains have been examined at the DNA
sequence level, but seldom using large-scale quantitative proteomics. We have compared …

Proteomic Insights Into Acinetobacter baumannii Drug Resistance and Pathogenesis

Q Long, C Huang, P Liao, J Xie - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Acinetobacter baumannii is an important opportunist pathogen, due to severe antibiotic
resistance and nosocomial infection. The epidemiology and antibiotic resistance of A …

Proteomic Analyses of Acinetobacter baumannii Clinical Isolates to Identify Drug Resistant Mechanism

P Wang, RQ Li, L Wang, WT Yang, QH Zou… - Frontiers in cellular and …, 2021 - frontiersin.org
Acinetobacter baumannii is one of the main causes of nosocomial infections. Increasing
numbers of multidrug-resistant Acinetobacter baumannii cases have been reported in recent …

Evolution of carbapenem-resistant Acinetobacter baumannii revealed through whole-genome sequencing and comparative genomic analysis

H Li, F Liu, Y Zhang, X Wang, C Zhao… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Acinetobacter baumannii is a globally important nosocomial pathogen characterized by an
evolving multidrug resistance. A total of 35 representative clinical A. baumannii strains …

Comparison of the outer membrane proteomes between clinical carbapenem‐resistant and ‐susceptible Acinetobacter baumannii

T Zhu, Z Lei, S Qu, F Zhao, L Yan… - Letters in Applied …, 2022 - Wiley Online Library
Abstract Background and Aim Carbapenem resistance has become a major obstacle in
combating Acinetobacter baumannii infections. Although enzymatic degradation by β …

Deciphering multifactorial resistance phenotypes in Acinetobacter baumannii by genomics and targeted label-free proteomics

T Cecchini, EJ Yoon, Y Charretier, C Bardet… - Molecular & Cellular …, 2018 - ASBMB
Resistance to β-lactams in Acinetobacter baumannii involves various mechanisms. To
decipher them, whole genome sequencing (WGS) and real-time quantitative polymerase …

Insights into the Periplasmic Proteins of Acinetobacter baumannii AB5075 and the Impact of Imipenem Exposure: A Proteomic Approach

D Scribano, V Marzano, S Levi Mortera… - International Journal of …, 2019 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii strains cause life-threatening infections due
to the lack of therapeutic options. Although the main mechanisms underlying antibiotic …

Transcriptome profiling in imipenem-selected Acinetobacter baumannii

KC Chang, HY Kuo, CY Tang, CW Chang, CW Lu… - BMC genomics, 2014 - Springer
Abstract Background Carbapenem-resistance in Acinetobacter baumannii has gradually
become a global challenge. To identify the genes involved in carbapenem resistance in A …

Carbapenem resistance in Acinetobacter baumannii: laboratory challenges, mechanistic insights and therapeutic strategies

I Abbott, GM Cerqueira, S Bhuiyan… - Expert review of anti …, 2013 - Taylor & Francis
Unprecedented levels of antimicrobial resistance in bacterial isolates have prompted great
concerns globally. In 2012 the WHO released a publication outlining the evolving threat of …