In recent years, there has been increasing interest in exploiting the effects of applied
pressure on biological systems. During the past few years, progress in research into the use …

Compared to temperature, the development of pressure as a tool in the research field has
emerged only recently (at the end of the XIXth century). Following several developments in …

Pressure is a thermodynamic parameter whose unique effects on biological systems are
increasingly being studied in a growing number of scientific fields. As such, the effects of …

Hydrostatic pressure is a well-known physical parameter which is now considered an
important variable of life, since organisms have the ability to adapt to pressure changes, by …

The effects of high hydrostatic pressure (up to 10 000 kg/cm 2) on the viability of
microorganisms and on protein denaturation have been known for over 90 years. Renewed …

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High-pressure (HP) biotechnology is an emerging technique initially applied for food
processing and more recently in pharmaceutical and medical sciences. Pressure can …

The effects of high pressure on various biological materials, such as the denaturation of
proteins, gelatinization of starches, and inactivation of enzymes, have been investigated for …

One century ago, the coagulation of egg white by applying pressure of 700 MPa showed for
the first time that pressure can denature a protein (PW Bridgman, J Biol Chem 19: 511–512 …

The first data in history on the effects of high hydrostatic pressure on organisms were most
likely compiled by Certes (1883) who found viable bacteria in water samples obtained from …