Background Mass administration of azithromycin for trachoma control led to a sustained
reduction in all-cause mortality among Ethiopian children. Whether the addition of …

Antibiotics with antimalarial activity may offer an interesting alternative for the treatment of
multidrug-resistant falciparum malaria. Azithromycin, a relatively recent semisynthetic …

In the course of our screening program to discover antimalarial antibiotics from soil
microorganisms which are active against drug-resistant parasites in vitro and in vivo, we …

This review concentrates on different aspects of malaria chemoprophylaxis, namely drug
combinations, resistance, impact of malaria prevention in pregnancy and cost effectiveness …

Azithromycin prevents malaria in animal models and early clinical trials. We determined the
prophylactic efficacy of three antibiotic regimens given for 10 weeks (azithromycin, 250 mg …

Macrolides are not used exclusively for the treatment of community-acquired respiratory tract
infections. Their ability to penetrate cells makes them highly suitable for the treatment of …

Abstract Objectives To evaluate Plasmodium malariae susceptibility to current and lead
candidate antimalarial drugs. Methods We conducted cross-sectional screening and …

Evidence of emerging Plasmodium falciparum resistance to artemisinin-based combination
therapies, documented in western Cambodia, underscores the continuing need to identify …

Reductions in malaria morbidity have been reported following azithromycin mass drug
administration (MDA) for trachoma. The recent Macrolides Oraux pour Reduire les Deces …

Available anti-malarial tools have over the ten-year period prior to 2012 dramatically
reduced the number of fatalities due to malaria from one million to less than six-hundred and …