Malaria in pregnancy is a substantial public health issue in many tropical countries.
However, its prevention and treatment have been hindered because of fears of adverse drug …

Background Resistance to front-line antimalarials (artemisinin combination therapies) is
spreading, and development of new drug treatment strategies to rapidly kill Plasmodium …

Antimalarial chemotherapy has become more complex and challenging because of
multidrug resistant strains of Plasmodium falciparum. Due to resistance of malarial parasite …

Malaria continues to be a major threat in the developing world, with> 1 million clinical
episodes and 3000 deaths every day. In the last century, malaria claimed between 150 and …

Novel classes of antimalarial drugs are needed due to emerging drug resistance.
Azithromycin, the first macrolide investigated for malaria treatment and prophylaxis, failed as …

Background To prevent the development of drug resistance, the World Health Organization
(WHO) recommends treating malaria with combination therapy. Azithromycin, an antibiotic …

Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …

Malaria remains one of the most deadly infectious diseases globally. Considering the
growing spread of resistance, development of new and effective antimalarials remains an …

Emerging drug resistance in Plasmodium falciparum and its rapid spread in endemic
countries have made the quest for new antimalarials a research priority. Tetracycline and its …

Bacterial and malaria co-infections are common in malaria endemic countries and thus
necessitate co-administration of antibiotics and antimalarials. There have long been …