Synthesis of three different amide-linked LNA-type dinucleotides and their incorporation into
9-mer and 17-mer oligodeoxynucleotides is described; compared to the reference DNA …

Thymin-1-yl-acetic acid and adenin-9-yl-acetic acid have been coupled to the N2′-atom of
a 2′-amino-LNA thymine nucleoside, and these “double-headed” LNA monomers have …

Oligodeoxynucleotides bearing 5′-appendages consisting of a nucleobase and an amide
linkage were prepared from 5′-amino-5′-deoxyoligonucleotides, amino acid building …

Mono-and diaminated 2′-amino-LNA monomers were synthesized and introduced into
oligonucleotides. Each modification imparts significant stabilization of nucleic acid duplexes …

Three α-l-ribofuranosyl analogues of RNA nucleotides (α-l-RNA analogues) have been
synthesized and incorporated into oligonucleotides using the phosphoramide approach on …

Triplex Formation with α-L-LNA (α-l-Ribo-Configured Locked Nucleic Acid) | Journal of the
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In this study, we characterize the thermodynamics of hybridization, binding kinetics and
conformations of four ribose-modified (2′-fluoro, 2′-O-propyl, 2′-O-methoxyethyl and 2 …

Synthesis of 3 '-3 '-linked oligonucleotides branched by a pentaerythritol linker is described.
The branched oligonucleotides were synthesized on a DNA/RNA synthesizer using a …

Synthesis of 2′-O, 4′-C-methylene-α-L-ribofuranosyl derivatives containing phenyl and 1-
pyrenyl aglycons, ie, novel α-L-ribo configured LNA-type C-aryl nucleosides, has been …

Synthesis of various N-acylated derivatives of 2′-amino-2′-deoxyuridine is described
together with their incorporation into DNA and LNA oligonucleotides using the …