Investigations of the homing of transplanted hemopoietic cells into preconditioned recipients
have in most studies been referable to parameters that determine engraftment. The …

Leukocytes move into tissues under three sets of guidelines. First, naive T and B cells have
a selective 'homing'pattern of migration via high endothelial venules (HEVs) into secondary …

Human hemopoietic blast colony-forming cells (BI-CFCs) recognize and adhere to the
extracellular matrix (ECM) produced by marrow-derived stromal cells in vitro. We have …

The mechanism of localization, migration, and regulation of hematopoiesis at different
stages of ontogeny is not well understood, but may relate to the specific adhesive …

The intercellular adhesion molecule (ICAM-1) is a cell-surface molecule which binds to
leukocyte function antigen-1 (LFA-1) and regulates both leukocyte adhesion to endothelial …

Hematopoietic stem cell interaction with elements of the underlying stroma is essential for
sustained normal hematopoiesis. Here we have determined that adhesion receptors in the …

The novel sialomucin, CD164, functions as both an adhesion receptor on human CD34+ cell
subsets in bone marrow and as a potent negative regulator of CD34+ hemopoietic …

The conditions that control the migratory status of hematopoietic progenitor cells on
extracellular matrix (ECM) and that decide whether a cell migrates or adheres are …

The past decade has given rise to a new view of vascular endothelium. Shrugging off its old
image as a simple bloodcompatible lining of vessels, it is now recognized as an active …

Cells of most tissues require adhesion to a surface to grow. However, for hematopoietic
cells, both stimulation and inhibition of proliferation by adhesion to extracellular matrix …