Adhesion of normal colony-forming cells (CFC) to bone marrow (BM) stroma and the
extracellular matrix (ECM) component fibronectin (FN) depends at least in part on the α4β1 …

The relationship between cell adhesion receptor expression on CD34+ cells in stem cell
grafts and the time to neutrophil and platelet recovery after autologous stem cell …

L-selectin, the peripheral lymph node “homing receptor,” is an adhesion protein that
mediates lymphocyte binding to lymph node high endothelial venules. Ligands for this …

The success of stem cell transplantation depends on the ability of iv infused stem cells to
engraft the bone marrow, a process referred to as homing. Efficient homing requires …

Cytokines are known to be important regulators of normal hemopoiesis, acting in concert
with components of the bone marrow microenvironment. Interactions with this …

Hematopoiesis takes place in close contact with the marrow microenvironment. Normal
progenitors adhere through a variety of receptors to stroma and extracellular matrix …

Leukocyte adhesion involves at least three molecular families of adhesion proteins: the
leukocyte integrins CD11/CD18, the intercellular adhesion molecules (ICAMs) and the …

Understanding the molecular basis of lymphocyte homing to lymphoid organs was originally
a problem of concern only to immunologists. With the discovery of l-selectin and its ligands …

Maintaining vascular integrity and defending against invasive pathogens require the rapid
regulation of adhesive interactions among blood cells and between blood cells and the …

P-selectin glycoprotein ligand-1 (PSGL-1) is a muclin-like glycoportein ligand for P-and E-
selectin on myeloid cells and a subset of lymphocytes. We used flow cytometry and …