Background. In recent studies increased amounts of nitric oxide (NO) and apoptosis have
been implicated in various pathological conditions in the kidney. We have studied the role of …

Background: There have been many studies in recent years concerning the role of nitric
oxide (NO) in acute renal failure (ARF). In this study, the effects of the inhibition or the …

Acute renal failure (ARF) either postischemic or neph-rotoxic is characterized by circulatory
changes and tubular injury that result in filtration failure. There are no unique mechanisms …

Nitric oxide synthase has been identified in several epithelial cells in the kidney, including
proximal tubular cells, thick ascending limb, inner medullary collecting duct, and interstitial …

Nitric oxide (NO) is generated from L-arginine (Arg) by different isoforms of nitric oxide
synthase (NOS) and plays a major role in maintaining the high basal renal blood flow. NO …

To determine the role of nitric oxide (NO) in acute renal failure (ARF), we have studied the
time course change activities to activity of nitric oxide synthase (NOS) isoform activities, both …

Renal mesangial cells exposed to inflammatory cytokines produce high concentrations of
nitric oxide (NO) which may exert cytotoxic actions. We report here that glomerular …

Nitric oxide (NO) shows an unusual divergence of action, being utilised both as a
physiological signalling molecule, and as a toxic mediator. NO-mediated cellular injury may …

Puromycin aminonucleoside (PAN) administration in rats produces an experimental model
of nephrotic syndrome characterized by glomerular epithelial cell injury and proteinuria. The …

BACKGROUND: The pathophysiology of renal ischaemia, resulting in tubular cell injury and
leading to acute renal failure (ARF), remains unclear. An ever-increasing number of …