Background Betaine is the trimethyl derivative of glycine and is normally present in human
plasma due to dietary intake and endogenous synthesis in liver and kidney. Betaine is …

Betaine, also known as trimethylglycine, is an important human nutrient obtained from a
variety of foods and also can be synthesized from choline. Betaine is much more abundant …

Betaine is distributed widely in animals, plants, and microorganisms, and rich dietary
sources include seafood, especially marine invertebrates (≈ 1%); wheat germ or bran (≈ …

Simple Summary A large number of studies report that medicinal herbs and many food
ingredients protect against the development of liver disease because they possess …

Betaine is an essential osmolyte and source of methyl groups and comes from either the diet
or by the oxidation of choline. Its metabolism methylates homocysteine to methionine, also …

The present review summarises the potential nutritional and physiological functions of
betaine as a feed additive in relation to performance criteria in livestock production. Betaine …

This review focuses on the metabolic and osmoregulatory functions of betaine and its impact
on nutrient digestibility and performance in pigs and poultry. Betaine is the trimethyl …

Tissue betaine is an intracellular osmolyte that also provides a store of labile methyl groups.
Despite these important biological roles, there are few data regarding tissue betaine content …

Two of the most important biochemical hepatic pathways in the liver are those that
synthesize methionine and S-adenosylmethionine (SAM) through the methylation of …

The possible physiological role of betaine, the oxidative product of choline, is considered. It
is proposed that betaine, instead of merely being a metabolic by-product of choline …