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The list of pathophysiological conditions associated with the overproduction of superoxide
expands every day. Much of the knowledge compiled on the role of this radical in disease …

(minireview). J Physiol Biochem, 65 (2), 195-208, 2009. Reactive oxygen species (ROS) are
known participants in several cellular processes. Superoxide anion radical, one example of …

An extensive search resulted in the identification of pamoic acid as an inhibitor of
superoxide dismutases. Pamoic acid appeared to rapidly and reversibly inhibit all types of …

Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

The lungs are directly exposed to higher oxygen concentrations than most other tissues.
Increased oxidative stress is a significant part of the pathogenesis of obstructive lung …

Publisher Summary The concept of oxidant-antioxidant balance seems to be emerging in
the free radical field. The remarkable ubiquity of superoxide dismutase (SOD) among …

Superoxide formation in pulmonary tissue is modulated by cytokines, Po2, shear force, and
disease states, and can be stimulated by drugs. Superoxide has diverse actions on …

Neutrophils play essential roles in several inflammatory reactions. Oxidant/antioxidant
imbalance is thought to be partially involved in the pathogenesis of the disorders. Under the …

M40403 is a low molecular weight, synthetic manganese containing superoxide dismutase
mimetic (SODm) that removes superoxide anions (. O2−) without interfering with other …