Bioprocess development for muconic acid production from aromatic compounds and lignin

D Salvachúa, CW Johnson, CA Singer, H Rohrer… - Green …, 2018 - pubs.rsc.org
Muconic acid (MA) is a bio-based platform chemical that can be converted into the
commodity petrochemical building blocks adipic acid or terephthalic acid, or used in …

Recent Advances in Microbial Production of cis,cis-Muconic Acid

S Choi, HN Lee, E Park, SJ Lee, ES Kim - Biomolecules, 2020 - mdpi.com
cis, cis-Muconic acid (MA) is a valuable C6 dicarboxylic acid platform chemical that is used
as a starting material for the production of various valuable polymers and drugs, including …

Biotechnological production of muconic acid: current status and future prospects

NZ Xie, H Liang, RB Huang, P Xu - Biotechnology advances, 2014 - Elsevier
Muconic acid (MA), a high value-added bio-product with reactive dicarboxylic groups and
conjugated double bonds, has garnered increasing interest owing to its potential …

From lignin to nylon: cascaded chemical and biochemical conversion using metabolically engineered Pseudomonas putida

M Kohlstedt, S Starck, N Barton, J Stolzenberger… - Metabolic …, 2018 - Elsevier
Cis, cis-muconic acid (MA) is a chemical that is recognized for its industrial value and is
synthetically accessible from aromatic compounds. This feature provides the attractive …

Glucose-Free cis,cis-Muconic Acid Production via New Metabolic Designs Corresponding to the Heterogeneity of Lignin

T Sonoki, K Takahashi, H Sugita… - ACS Sustainable …, 2018 - ACS Publications
Lignin conversion to value-added products is one of the most attractive challenges to
develop a complete system for lignocellulosic biomass utilization. The objective of this study …

Muconic Acid Production Using Engineered Pseudomonas putida KT2440 and a Guaiacol-Rich Fraction Derived from Kraft Lignin

H Almqvist, H Veras, K Li… - ACS Sustainable …, 2021 - ACS Publications
Industrial lignin such as kraft lignin is an abundant feedstock for renewable chemicals and
materials. In this study, a process was developed for depolymerization of kraft lignin followed …

Metabolic engineering of Corynebacterium glutamicum for the production of cis, cis-muconic acid from lignin

J Becker, M Kuhl, M Kohlstedt, S Starck… - Microbial cell …, 2018 - Springer
Background Cis, cis-muconic acid (MA) is a dicarboxylic acid of recognized industrial value.
It provides direct access to adipic acid and terephthalic acid, prominent monomers of …

[HTML][HTML] Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics

F Weiland, N Barton, M Kohlstedt, J Becker… - Metabolic …, 2023 - Elsevier
Lignin displays a highly challenging renewable. To date, massive amounts of lignin,
generated in lignocellulosic processing facilities, are for the most part merely burned due to …

Debottlenecking 4-hydroxybenzoate hydroxylation in Pseudomonas putida KT2440 improves muconate productivity from p-coumarate

E Kuatsjah, CW Johnson, D Salvachúa, AZ Werner… - Metabolic …, 2022 - Elsevier
Abstract The transformation of 4-hydroxybenzoate (4-HBA) to protocatechuate (PCA) is
catalyzed by flavoprotein oxygenases known as para-hydroxybenzoate-3-hydroxylases …

Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440

GJ Bentley, N Narayanan, RK Jha, D Salvachúa… - Metabolic …, 2020 - Elsevier
Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst
for the conversion of diverse carbon sources to multiple products, including the olefinic …