The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides
widely distributed in the mammalian central and peripheral nervous system. In the …

Molecular aspects of the tachykinin receptors Page 1 Regulatory Peptides, 43 (1993) 21-35
21 й 1993 Elsevier Science Publishers BV All rights reserved 0167-0115/93/$06.00 …

The last decade has witnessed major breakthroughs in the study of tachykinin receptors.
The currently described NK-1, NK-2, and NK-3 receptors have been sequenced and cloned …

The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …

The use of selective agonists in both functional and binding studies has provided
unequivocal evidence for the existence of three types of tachykinin receptor (NK 1, NK 2 and …

Tachykinins are a family of peptides that share the common C-terminal sequence, Phe-X-Gly-
Leu-Met-NH,. In mammals, at least three different tachykinins, namely, substance P (SP) …

Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

Besides Substance P (SP)[I], two tachykinins have been isolated from the brain and the
spinal cord of mammals, ie Neurokinin A (NKA, also named Substance K and Neuromedin …

Fig. 1. A serpentine model of the NK1 receptor and structures of human tachykinin peptides
and some relevant analogues. For the ligands, the residues corresponding to the substance …

A family of peptides that shares a common C-terminal sequence (Phe-X-Gly-Leu-MetNH 2)
exists in mammalian and non-mammalian species. In mammals, three of these peptides …