Cetuximab therapy for head and neck squamous cell carcinoma: a systematic review of the data
TD Reeves, EG Hill, KE Armeson… - … --Head and Neck …, 2011 - journals.sagepub.com
Objective. To review the current state of the data on the use of cetuximab in head and neck
squamous cell carcinoma (HNSCC). Data Sources. The National Center for Biotechnology …
squamous cell carcinoma (HNSCC). Data Sources. The National Center for Biotechnology …
Phase I study of cetuximab in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in patients (pts) with recurrent and/or metastatic squamous cell …
Y Humblet, E Vega-Villegas, R Mesia… - Journal of Clinical …, 2004 - ascopubs.org
5513 Background: The goal of this study was to investigate the safety and efficacy of
cetuximab (Erbitux), an IgG1 monoclonal antibody targeting the EGFR, given in combination …
cetuximab (Erbitux), an IgG1 monoclonal antibody targeting the EGFR, given in combination …
Phase I/II study of cetuximab in combination with cisplatin or carboplatin and fluorouracil in patients with recurrent or metastatic squamous cell carcinoma of the head …
J Bourhis, F Rivera, R Mesia, A Awada… - Journal of clinical …, 2006 - ascopubs.org
Purpose This was an open, randomized, multicenter, phase I/II study to investigate the safety
and tolerability of cetuximab in the first-line treatment of recurrent/metastatic squamous cell …
and tolerability of cetuximab in the first-line treatment of recurrent/metastatic squamous cell …
Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: A phase III study of high dose radiation therapy with …
JA Bonner, PM Harari, J Giralt, N Azarnia… - Journal of Clinical …, 2004 - ascopubs.org
5507 Background: The majority of head and neck cancers overexpress the epidermal
growth factor receptor (EGFR), which is associated with aggressive tumor behavior and poor …
growth factor receptor (EGFR), which is associated with aggressive tumor behavior and poor …
Is the combination of Cetuximab with chemo-radiotherapy regimens worthwhile in the treatment of locally advanced head and neck cancer? A review of current …
G Numico, P Franco, A Cristofano, F Migliaccio… - Critical reviews in …, 2013 - Elsevier
The administration of Cetuximab in combination with radiotherapy and chemotherapy has
shown clear survival improvements within the locally advanced and the relapsed/metastatic …
shown clear survival improvements within the locally advanced and the relapsed/metastatic …
A randomized phase II study of cetuximab every 2 weeks at either 500 or 750 mg/m2 for patients with recurrent or metastatic head and neck squamous cell cancer
Cetuximab is typically administered on a weekly schedule for patients with recurrent or
metastatic head and neck squamous cell cancer (HNSCC). This study explores cetuximab …
metastatic head and neck squamous cell cancer (HNSCC). This study explores cetuximab …
EGFR monoclonal antibodies in the treatment of squamous cell carcinoma of the head and neck: a view beyond cetuximab
SA Kono, M Haigentz Jr, SS Yom… - … Research and Practice, 2012 - Wiley Online Library
Squamous cell carcinoma of the head and neck (SCCHN) is a prevalent disease both in the
United States and worldwide with an overall poor prognosis, in part due to limited activity of …
United States and worldwide with an overall poor prognosis, in part due to limited activity of …
Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro
N Zhang, K Erjala, J Kulmala, X Qiu, M Sundvall… - Radiotherapy and …, 2009 - Elsevier
BACKGROUND AND PURPOSE: For locoregionally advanced HNSCC, chemoradiotherapy
with cisplatin or another platinum compound is considered as one of the standard treatment …
with cisplatin or another platinum compound is considered as one of the standard treatment …
Cetuximab in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in the first-line treatment of patients with recurrent and/or metastatic squamous cell …
JB Vermorken, R Mesia, ME Vega-Villegas… - Journal of Clinical …, 2006 - ascopubs.org
5537 Background: The epidermal growth factor receptor (EGFR) is expressed in nearly all
SCCHN and carries a strong prognostic significance, providing the rationale for using EGFR …
SCCHN and carries a strong prognostic significance, providing the rationale for using EGFR …
Cetuximab and the head and neck squamous cell cancer
R Concu, M Cordeiro - Current topics in medicinal chemistry, 2018 - ingentaconnect.com
The Head and Neck Squamous Cell Cancer (HNSCC) is the most common type of head and
neck cancer (more than 90%), and all over the world more than a half million people have …
neck cancer (more than 90%), and all over the world more than a half million people have …