An extraretinally expressed insect cryptochrome with similarity to the blue light photoreceptors of mammals and plants

ES Egan, TM Franklin… - Journal of …, 1999 - Soc Neuroscience
Photic entrainment of insect circadian rhythms can occur through either extraretinal (brain)
or retinal photoreceptors, which mediate sensitivity to blue light or longer wavelengths …

The Blue-Light Photoreceptor CRYPTOCHROME Is Expressed in a Subset of Circadian Oscillator Neurons in the Drosophila CNS

J Benito, JH Houl, GW Roman… - Journal of biological …, 2008 - journals.sagepub.com
In the fruit fly Drosophila melanogaster, CRYPTOCHROME (CRY) functions as a
photoreceptor to entrain circadian oscillators to light-dark cycles and as a transcription factor …

The two CRYs of the butterfly

H Zhu, Q Yuan, O Froy, A Casselman, SM Reppert - Current Biology, 2005 - cell.com
Animal flavoproteins called cryptochromes (CRYs) are generally believed to have distinct
circadian clock functions in insects and mammals: Drosophila has one CRY (dCRY) which …

Drosophila CRY is a deep brain circadian photoreceptor

P Emery, R Stanewsky, C Helfrich-Förster, M Emery-Le… - Neuron, 2000 - cell.com
Abstract cry (cryptochrome) is an important clock gene, and recent data indicate that it
encodes a critical circadian photoreceptor in Drosophila. A mutant allele, cry b, inhibits …

Cryptochromes: sensory reception, transduction, and clock functions subserving circadian systems

JC Hall - Current opinion in neurobiology, 2000 - Elsevier
Cryptochromes (CRYs) are blue-light-absorbing proteins involved in a variety of biological
phenomena. In animals, CRYs exhibit a certain versatility with regard to these organisms' …

Novel features of cryptochrome-mediated photoreception in the brain circadian clock of Drosophila

A Klarsfeld, S Malpel, C Michard-Vanhée… - Journal of …, 2004 - Soc Neuroscience
In Drosophila, light affects circadian behavioral rhythms via at least two distinct mechanisms.
One of them relies on the visual phototransduction cascade. The other involves a …

Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock in Drosophila melanogaster

M Schlichting, D Rieger, P Cusumano… - Frontiers in molecular …, 2018 - frontiersin.org
Cryptochromes (CRYs) are a class of flavoproteins that sense blue light. In animals, CRYs
are expressed in the eyes and in the clock neurons that control sleep/wake cycles and are …

CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity

P Emery, WV So, M Kaneko, JC Hall, M Rosbash - Cell, 1998 - cell.com
Light is a major environmental signal for circadian rhythms. We have identified and analyzed
cry, a novel Drosophila cryptochrome gene. All characterized family members are directly …

Light‐dependent reactions of animal circadian photoreceptor cryptochrome

N Ozturk - The FEBS Journal, 2022 - Wiley Online Library
Circadian rhythms are endogenous autonomous 24‐h oscillations that are generated by a
transcription–translation feedback loop (TTFL). In the positive arm of the TTFL, two …

Light entrainment of retinal biorhythms: cryptochrome 2 as candidate photoreceptor in mammals

J Vanderstraeten, P Gailly, EP Malkemper - Cellular and Molecular Life …, 2020 - Springer
The mechanisms that synchronize the biorhythms of the mammalian retina with the light/dark
cycle are independent of those synchronizing the rhythms in the central pacemaker, the …