Introduction Evidence is lacking on withdrawal syndrome related to individual
antidepressants and relevant risk factors for severe reactions. Objective To ascertain …

ContextAlthough current depression treatment guidelines recommend continuing
antidepressant therapy for at least 4 to 9 months, many patients discontinue treatment …

Accessible Summary What is known on the subject? Rates of antidepressant prescribing
have been increasing. Antidepressants are not effective for many people. What the paper …

Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

Approximately half of the tens of millions of people currently taking antidepressants will
experience withdrawal symptoms when they try to reduce or come off them. Nearly half of …

Depressive illness is now recognised as a major health problem. As many patients do not
need indefinite treatment, clinicians need to be aware of the symptoms associated with the …

Objective: Prior efforts to assess the impact of antidepressant use on risk of suicide attempt
focused on antidepressant initiation or duration of use. Gaps remain in understanding risks …

Background The topic of patients' discontinuing use of antidepressants has received
increasing attention. Patients and physicians can encounter challenges regarding the three …

Studies have suggested that discontinuation of treatment in depressed patients is
associated with their perceptions about their treatment. We surveyed 403 adults treated for …

Long-term antidepressant treatment has increased and there is evidence of adverse effects;
however, little is known about patients' experiences and views of this form of treatment. This …