With aging, there is increased dysfunction of both innate and adaptive immune responses,
which contributes to impaired immune responses to pathogens and greater mortality and …

Cellular senescence is a critical part of human anti-tumor defence; however, the
accumulation of senescent cells with age underpins a wide range of pathologies. Senescent …

Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms
are linked to innate and adaptive immune dysfunction that accompanies aging (known as …

The function of the immune system declines during aging, compromising its response
against pathogens, a phenomenon termed as “immunosenescence.” Alterations of the …

The ageing of the global population brings about unprecedented challenges. Chronic age‐
related diseases in an increasing number of people represent an enormous burden for …

Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

From a holistic point of view, aging results from the cumulative erosion of the various
systems. Among these, the immune system is interconnected to the rest as immune cells are …

Immunosenescence is a multi-faceted phenomenon at the root of age-associated immune
dysfunction. It can lead to an array of pathological conditions, including but not limited to a …

Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …

Immunosenescence, describing alterations, including decline of immune responses with
age, is comprised of inappropriate elevations, decreases, and dysregulated immune …