A melastatin-like transient receptor potential 2 (TRPM2) channel is activated in concert with
Ca 2+ by intracellular adenosine diphosphoribose (ADPR) binding to the channel's enzyme …

Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential
(TRPM2) cation channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ …

The melastatin-related transient receptor potential channel TRPM2 is a plasma membrane
Ca 2+-permeable cation channel that is activated by intracellular adenosine …

Melastatin-like transient receptor potential 2 (TRPM2) channel is a redox sensitive Ca2+-
permeable cation channel that can be gated by H2O2 binding to the channel's enzymatic …

Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential 2
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …

Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …

Microglial cells are the host macrophages in the central nervous system and respond to
brain injury and various neurological diseases. In this process, microglial cells undergo …

TRPM2 is a calcium-permeable nonselective cation channel that is opened by the binding of
ADP-ribose (ADPR) to a C-terminal nudix domain. Channel activity is further regulated by …

A unique functional property within the transient receptor potential (TRP) family of cation
channels is the gating of TRP (melastatin) 2 (TRPM2) channels by ADP-ribose (ADPR) …

TRPM2 is a calcium‐permeable non‐selective cation channel expressed in the plasma
membrane and in lysosomes that is critically involved in aggravating reactive oxygen …