The etiologic agent of plague, Yersinia pestis, is a globally distributed pathogen which
poses both a natural and adversarial threat. Due largely to the rapid course and high …

Three great plague pandemics caused by the gram-negative bacterium Yersinia pestis have
killed nearly 200 million people and it has been linked to biowarfare in the past. Plague is …

The risk of plague as a bioweapon has prompted increasing research efforts to develop
plague vaccines due to its extreme virulence and the ease of its transmission. Subunit …

Three great plague pandemics caused by the gram-negative bacterium Yersinia pestis have
killed nearly 200 million people and it has been linked to biowarfare in the past. Plague is …

Plague caused by Yersinia pestis is one of the most dangerous infectious diseases. There is
no ideal plague vaccine available for human use, but a number of licensed killed whole-cell …

Current subunit vaccines provide partial protection against pneumonic plague if the infecting
Y. pestis strain is encapsulated (F1+). Here we describe YadC, a novel Y. pestis outer …

Yersinia pestis, the causative agent of plague, is a potential weapon of bioterrorism. Y.
pestis evades the innate immune system by synthesizing tetra-acylated lipid A with poor Toll …

In a search for novel attenuated vaccine candidates for use against Yersinia pestis, the
causative agent of plague, a signature-tagged mutagenesis strategy was used and …

An in-frame deletion of the yopH gene in Yersinia pestis CO92 attenuates virulence in both
bubonic and pneumonic plague models. When it is used as a live, attenuated vaccine …

V antigen of Yersinia pestis is a multifunctional protein that has been implicated as a
protective antigen, a virulence factor, and a regulatory protein. A series of V-antigen …