Irregular high frequency patterns decrease the effectiveness of deep brain stimulation in a rat model of Parkinson's disease
RQ So, GC McConnell, JD Hilliard… - 2011 5th International …, 2011 - ieeexplore.ieee.org
Deep brain stimulation (DBS) is an effective treatment of Parkinson's disease, but its
mechanisms are still unclear. To test the hypothesis that DBS alleviates motor symptoms by …
mechanisms are still unclear. To test the hypothesis that DBS alleviates motor symptoms by …
Improved efficacy of temporally non-regular deep brain stimulation in Parkinson's disease
High frequency deep brain stimulation is an effective therapy for motor symptoms in
Parkinson's disease. However, the relative clinical efficacy of regular versus non-regular …
Parkinson's disease. However, the relative clinical efficacy of regular versus non-regular …
Patterned low-frequency deep brain stimulation induces motor deficits and modulates cortex-basal ganglia neural activity in healthy rats
CS Oza, DT Brocker, CE Behrend… - Journal of …, 2018 - journals.physiology.org
Deep brain stimulation (DBS) is an effective therapy for movement disorders, including
Parkinson's disease (PD), although the mechanisms of action remain unclear. Abnormal …
Parkinson's disease (PD), although the mechanisms of action remain unclear. Abnormal …
Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns
GC McConnell, RQ So, JD Hilliard… - Journal of …, 2012 - Soc Neuroscience
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for
the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on …
the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on …
Multiple stimulation parameters influence efficacy of deep brain stimulation in parkinsonian mice
Deep brain stimulation (DBS) is used to treat multiple neuropsychiatric disorders, including
Parkinson's disease (PD). Despite widespread clinical use, its therapeutic mechanisms are …
Parkinson's disease (PD). Despite widespread clinical use, its therapeutic mechanisms are …
Theta-phase closed-loop stimulation induces motor paradoxical responses in the rat model of Parkinson disease
Background High-frequency deep brain stimulation (DBS) has become a widespread
therapy used in the treatment of Parkinson's Disease (PD) and other diseases. Although it …
therapy used in the treatment of Parkinson's Disease (PD) and other diseases. Although it …
Failure to suppress low-frequency neuronal oscillatory activity underlies the reduced effectiveness of random patterns of deep brain stimulation
Subthalamic nucleus (STN) deep brain stimulation (DBS) is an established treatment for the
motor symptoms of Parkinson's disease (PD). However, the mechanisms of action of DBS …
motor symptoms of Parkinson's disease (PD). However, the mechanisms of action of DBS …
Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation
S Li, GW Arbuthnott, MJ Jutras… - Journal of …, 2007 - journals.physiology.org
Deep brain stimulation (DBS) is an effective treatment of Parkinson's disease (PD) for many
patients. The most effective stimulation consists of high-frequency biphasic stimulation …
patients. The most effective stimulation consists of high-frequency biphasic stimulation …
Deep brain stimulation in Parkinson's disease can mimic the 300 Hz subthalamic rhythm
We read with much interest the paper by Meissner et al.(2005) recently published in Brain.
The authors provided neurophysiological evidence that in MPTP-treated monkeys high …
The authors provided neurophysiological evidence that in MPTP-treated monkeys high …
A perspective on the use of high-frequency stimulation in deep brain stimulation for Parkinson's disease
Parkinson's disease is a neurodegenerative disorder of the central nervous system and
among the symptoms, rest tremors is one of the key symptoms. Deep Brain Stimulation …
among the symptoms, rest tremors is one of the key symptoms. Deep Brain Stimulation …
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