Abstract▴ Estradiol valerate/dienogest is an oral contraceptive for women that combines the
natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic …

Objective: To review the pharmacology, pharmacokinetics, efficacy, and safety of the new
oral contraceptive estradiol valerate/dienogest. Data Sources: Searches of PubMed (1966 …

Most combination oral contraceptives contain ethinyl estradiol and a progestin. A new and
novel oral contraceptive formulation combines estradiol valerate (E2V) with dienogest …

BACKGROUND: Estradiol valerate/dienogest (E2V/DNG) is a combined oral contraceptive
(COC) with 2 new hormonal entities and a unique 4-phasic dosing regimen indicated for …

OBJECTIVE: A novel oral contraceptive (OC) that contains oestradiol valerate (E2V; 1mg of
E2V is equivalent to 0.76 mg of 17beta-oestradiol) and dienogest (DNG) has been …

Background To investigate the efficacy and safety of a combined oral contraceptive
containing estradiol valerate and dienogest (EV/DNG) in healthy Asian women. Methods In …

Importance of the field: Since ethinyl estradiol is a potent activator of hepatic enzymes, the
use of natural estradiol (E2) has been studied; but, until recently, bleeding control has …

Natural estrogens such as estradiol (E2) or its valerate ester (E2V) offer an alternative to
ethinyl estradiol (EE). E2-containing combined oral contraceptives (COCs) have …

Background: This study investigated the efficacy and safety of a combined oral contraceptive
(COC) containing estradiol valerate/dienogest (E2V/DNG). Methods: This was a multicenter …

Three estradiol (E2)-containing oral contraceptives, estradiol valerate/cyproterone acetate
(E2V/CPA, Femilar®), estradiol valerate/dienogest (E2V/DNG, Qlaira®/NataziaTM), and …