Challenges and controversies concerning Neisseria gonorrhoeae-neutrophil interactions in pathogenesis

AK Criss, CA Genco, SD Gray-Owen, AE Jerse… - MBio, 2021 - Am Soc Microbiol
ABSTRACT The bacterium Neisseria gonorrhoeae (Ngo) is the main cause of the sexually
transmitted infection gonorrhea. The global incidence of 87 million new Ngo infections each …

Neisseria gonorrhoeae downregulates expression of the human antimicrobial peptide LL‐37

P Bergman, L Johansson, V Asp, L Plant… - Cellular …, 2005 - Wiley Online Library
Neisseria gonorrhoeae is a human pathogen causing the sexually transmitted disease
gonorrhoeae. The bacteria preferentially attach to and invade epithelial cells of the genital …

[HTML][HTML] Macrophage–Neisseria gonorrhoeae interactions: a better understanding of pathogen mechanisms of immunomodulation

A Escobar, PI Rodas, C Acuña-Castillo - Frontiers in immunology, 2018 - frontiersin.org
Neisseria gonorrhoeae is a significant health problem worldwide due to multi-drug
resistance issues and absence of an effective vaccine. Patients infected with N …

Characterization of Neisseria gonorrhoeae colonization of macrophages under distinct polarization states and nutrients environment

MD Juárez Rodríguez, M Marquette… - Frontiers in Cellular …, 2024 - frontiersin.org
Neisseria gonorrhoeae (Ng) is a uniquely adapted human pathogen and the etiological
agent of gonorrhea, a sexually transmitted disease. Ng has developed numerous …

Isolation of Cell Envelopes and Naturally Released Membrane Vesicles of Neisseria gonorrhoeae

RA Zielke, AE Sikora - Current Protocols in Microbiology, 2014 - Wiley Online Library
Neisseria gonorrhoeae (GC) is a strict human pathogen and the agent of the sexually
transmitted disease gonorrhea. Gonococcal infections have been successfully treated with …

Regulatory T Cells Are Locally Induced during Intravaginal Infection of Mice with Neisseria gonorrhoeae

M Imarai, E Candia, C Rodriguez-Tirado… - Infection and …, 2008 - Am Soc Microbiol
Neisseria gonorrhoeae is a gram-negative diplococcus that in human beings produces
gonorrhea. Much clinical evidence has led to the conclusion that gonococcus has important …

[HTML][HTML] Neisseria gonorrhoeae MlaA influences gonococcal virulence and membrane vesicle production

BI Baarda, RA Zielke, A Le Van, AE Jerse… - Plos …, 2019 - journals.plos.org
The six-component maintenance of lipid asymmetry (Mla) system is responsible for
retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell …

Trichomonas vaginalis Induces SiHa Cell Apoptosis by NF‐κB Inactivation via Reactive Oxygen Species

JH Quan, BH Kang, JB Yang, YE Rhee… - BioMed Research …, 2017 - Wiley Online Library
Trichomonas vaginalis induces apoptosis in host cells through various mechanisms;
however, little is known about the relationship between apoptosis, reactive oxygen species …

Neisseria gonorrhoeae Coordinately Uses Pili and Opa To Activate HEC-1-B Cell Microvilli, Which Causes Engulfment of the Gonococci

JML Griffiss, CJ Lammel, J Wang, NP Dekker… - Infection and …, 1999 - Am Soc Microbiol
This study was undertaken to examine concomitant roles of pili and colony opacity-
associated proteins (Opa) in promoting Neisseria gonorrhoeae adherence to and invasion …

[HTML][HTML] Suppression of host adaptive immune responses by Neisseria gonorrhoeae: role of interleukin 10 and type 1 regulatory T cells

Y Liu, W Liu, MW Russell - Mucosal immunology, 2014 - Elsevier
Infection with Neisseria gonorrhoeae triggers an intense inflammatory response
characterized by an influx of neutrophils in the genital tract, yet natural gonococcal infection …