Infection of mucosal epithelial cells by Neisseria gonorrhoeae

JPM van Putten, TD Duensing - Reviews and Research in …, 1997 - journals.lww.com
The bacterial pathogen Neisseria gonorrhoeae (gonococcus) is able to colonize and
penetrate the human mucosa, to avoid the host's defences and to persist in various …

Mouse Strain-Dependent Differences in Susceptibility to Neisseria gonorrhoeae Infection and Induction of Innate Immune Responses

M Packiam, SJ Veit, DJ Anderson, RR Ingalls… - Infection and …, 2010 - Am Soc Microbiol
Acute gonorrhea in women is characterized by a mucopurulent exudate that contains
polymorphonuclear leukocytes (PMNs) with intracellular gonococci. Asymptomatic infections …

[图书][B] Neisseria gonorrhoeae: methods and protocols

M Christodoulides - 2019 - Springer
This detailed book addresses the continual development and application of new methods
and protocols to understand the biology of the pathogen Neisseria gonorrhoeae. Beginning …

Engulfment of Neisseria gonorrhoeae: Revealing Distinct Processes of Bacterial Entry by Individual Carcinoembryonic Antigen-Related Cellular Adhesion Molecule …

SE McCaw, EH Liao, SD Gray-Owen - Infection and immunity, 2004 - Am Soc Microbiol
Individual Neisseria gonorrhoeae colony opacity-associated (Opa) protein variants can bind
up to four different carcinoembryonic antigen-related cellular adhesion molecule (CEACAM) …

[HTML][HTML] The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice

EA Islam, Y Shaik-Dasthagirisaheb, C Kaushic… - Mucosal …, 2016 - Elsevier
Women with asymptomatic Neisseria gonorrhoeae infection are at risk of developing pelvic
inflammatory disease (PID) if the bacteria ascend from the endocervix into the uterus and …

Neisseria gonorrhoeae Epithelial Cell Interaction Leads to the Activation of the Transcription Factors Nuclear Factor κB and Activator Protein 1 and the Induction of …

M Naumann, S Weßler, C Bartsch, B Wieland… - The Journal of …, 1997 - rupress.org
We have studied the effect of human bacterial pathogen Neisseria gonorrhoeae (Ngo) on
the activation of nuclear factor (NF)-κB and the transcriptional activation of inflammatory …

Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development

PA Rice, WM Shafer, S Ram… - Annual review of …, 2017 - annualreviews.org
Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …

Gonococcal pathogenesis: adaptation and immune evasion in the human host

TM Alcorn, MS Cohen - Current Opinion in Infectious Diseases, 1994 - journals.lww.com
Neisseria gonorrhoeae is a mucosal pathogen limited to the human host. Infection with
gonococci does not elicit protective immunity. The pathogenesis of gonococcal infection …

Female Mouse Model of Neisseria gonorrhoeae Infection

EL Raterman, AE Jerse - Neisseria gonorrhoeae: methods and protocols, 2019 - Springer
Mouse models of infection are important tools in the study of infectious disease or host the
development of products to prevent or treat infections. The estradiol-treated mouse model of …

Preclinical testing of vaccines and therapeutics for gonorrhea in female mouse models of lower and upper reproductive tract infection

KL Connolly, M Pilligua-Lucas, C Gomez… - The Journal of …, 2021 - academic.oup.com
Murine models of Neisseria gonorrhoeae lower reproductive tract infection are valuable
systems for studying N. gonorrhoeae adaptation to the female host and immune responses …