[HTML][HTML] Neisseria gonorrhoeae employs two protein inhibitors to evade killing by human lysozyme

SA Ragland, MV Humbert, M Christodoulides… - PLoS …, 2018 - journals.plos.org
The bacterial pathogen Neisseria gonorrhoeae (Gc) infects mucosal sites rich in
antimicrobial proteins, including the bacterial cell wall-degrading enzyme lysozyme. Certain …

Neisseria gonorrhoeae physiology and pathogenesis

LR Green, J Cole, EFD Parga, JG Shaw - Advances in microbial physiology, 2022 - Elsevier
Neisseria gonorrhoeae is an obligate human pathogen that is the cause of the sexually
transmitted disease gonorrhoea. Recently, there has been a surge in gonorrhoea cases that …

The role of complement receptor 3 (CR3) in Neisseria gonorrhoeae infection of human cervical epithelia

JL Edwards, EJ Brown, KA Ault… - Cellular …, 2001 - Wiley Online Library
Neisseria gonorrhoeae is an important sexually transmitted pathogen and a major cofactor
in HIV‐1 infection. This organism uses different mechanisms to infect male and female …

The ticking time bomb: escalating antibiotic resistance in Neisseria gonorrhoeae is a public health disaster in waiting

DM Whiley, N Goire, MM Lahra… - Journal of …, 2012 - academic.oup.com
From a once easily treatable infection, gonorrhoea has evolved into a challenging disease,
which in future may become untreatable in certain circumstances. International spread of …

[HTML][HTML] Epithelial haven and autophagy breakout in gonococci infection

AC Mendes, M Ciccone, B Gazolla… - Frontiers in cell and …, 2020 - frontiersin.org
The World Health Organization (WHO) has estimated that in 2016, there were 87 million new
cases of gonorrhea. Gonorrhea is caused by the sexually transmitted human-exclusive …

Colonization efficiency of multidrug-resistant Neisseria gonorrhoeae in a female mouse model

B Kikiowo, AB Bandara, NS Abutaleb… - Pathogens and …, 2023 - academic.oup.com
The rapid occurrence of gonococcal resistance to all classes of antibiotics could lead to
untreatable gonorrhea. Thus, development of novel anti-Neisseria gonorrhoeae drugs is …

Immortalization of Human Urethral Epithelial Cells: a Model for the Study of the Pathogenesis of and the Inflammatory Cytokine Response to Neisseria gonorrhoeae …

HA Harvey, DMB Post, MA Apicella - Infection and immunity, 2002 - Am Soc Microbiol
The primary human urethral epithelial cells developed by our laboratory have been
immortalized by transduction with a retroviral vector expressing the human papillomavirus …

Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae

JS Stevens, AK Criss - Current opinion in hematology, 2018 - journals.lww.com
Pathogenesis of Neisseria gonorrhoeae in the female reproduc... : Current Opinion in
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …

Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae

H Sarantis, SD Gray-Owen - Infection and immunity, 2012 - Am Soc Microbiol
Symptomatic infection of humans with Neisseria gonorrhoeae is characterized by a
neutrophil-rich cervical or urethral exudate, suggesting that neutrophils are important both …

[HTML][HTML] Phase Variation Leads to the Misidentification of a Neisseria Gonorrhoeae Virulence Gene

MT Anderson, HS Seifert - PloS one, 2013 - journals.plos.org
Neisseria gonorrhoeae is the causative agent of gonorrhea and an obligate pathogen of
humans. The Opa proteins of these bacteria are known to mediate attachment and …