Selective recognition of G-quadruplexes by a dimeric carbocyanine dye

P Chilka, PR Patlolla, B Datta - RSC advances, 2016 - pubs.rsc.org
A novel dimeric carbocyanine dye is found to recognise G-quadruplex structures selectively
compared to mixed sequence or double-stranded DNA molecules. The dye exhibits a …

A comparative study for recognizing G-quadruplexes using dimeric cyanine dyes with different sizes of aromatic substituents

L Yu, Q Yang, J Xiang, Y Tang - Analytical methods, 2015 - pubs.rsc.org
A series of dimeric cyanine dyes with different sizes of heterocyclic aromatic substituents
and the same linker were synthesized, and these dyes were demonstrated to be highly …

Triphenylmethane dyes as fluorescent probes for G-quadruplex recognition

JH Guo, LN Zhu, DM Kong, HX Shen - Talanta, 2009 - Elsevier
Triphenylmethane (TPM) dyes normally render rather weak fluorescence due to easy
vibrational deexcitation. However, when they stack onto the two external G-quartets of a G …

Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G …

Q Yang, J Xiang, S Yang, Q Li, Q Zhou… - Nucleic acids …, 2010 - academic.oup.com
The supramolecular assembly of a novel cyanine dye, 3, 3′-di (3-sulfopropyl)-4, 5, 4′, 5′-
dibenzo-9-ethyl-thiacarbocyanine triethylammonium salt (ETC) was designed to verify …

Targeting of parallel c-myc G-quadruplex by dimeric cyanine dye supramolecular assembly: dependence on the linker length

L Yu, Q Yang, J Xiang, H Sun, L Wang, Q Li, A Guan… - Analyst, 2015 - pubs.rsc.org
A series of dimeric cyanine dyes were designed to study their recognition for parallel c-myc
G-quadruplex as well as their spectral features in solution. Dimeric cyanine dyes having …

Molecular recognition and visual detection of G‐quadruplexes by a dicarbocyanine dye

B Karg, A Funke, A Ficht… - … A European Journal, 2015 - Wiley Online Library
The interactions of a dicarbocyanine dye 3, 3′‐diethylthiadicarbocyanine, DiSC2 (5), with
DNA G‐quadruplexes were studied by means of a combination of various spectroscopic …

Noncovalent binding and fluorogenic response of cyanine dyes to DNA homoquadruplex and PNA-DNA heteroquadruplex structures

HS Mohammed, JO Delos Santos… - Artificial DNA: PNA & …, 2011 - Taylor & Francis
Two symmetrical cyanine dyes based on benzothiazole heterocycles and a trimethine
bridge were found to bind to a parallel-stranded DNA guanine quadruplex based on the …

Fluorescent sensor for monitoring structural changes of G-quadruplexes and detection of potassium ion

DM Kong, YE Ma, JH Guo, W Yang… - Analytical chemistry, 2009 - ACS Publications
G-rich sequences with the potential for quadruplex formation are common in genomic DNA.
Considering that the biological functions of G-quadruplexes may well depend on their …

A simple structural modification to thiazole orange to improve the selective detection of G-quadruplexes

RJ Guo, JW Yan, SB Chen, LQ Gu, ZS Huang, JH Tan - Dyes and Pigments, 2016 - Elsevier
Thiazole orange is a commonly used cyanine dye for binding to nucleic acids. Recently, it
has been used for the detection of G-quadruplexes. However, thiazole orange is non …

Tuning the selectivity of a commercial cyanine nucleic acid dye for preferential sensing of hybrid telomeric G-quadruplex DNA

YQ Wang, MH Hu, RJ Guo, SB Chen, ZS Huang… - Sensors and Actuators B …, 2018 - Elsevier
Recent years have witnessed an ever-increasing interest in G-quadruplexes for diagnostic
and therapeutic applications. This calls for the development of highly selective probes that …