The role of adiponectin in the pathogenesis of the metabolic syndrome and approach to therapy

AV Rodina, SE Severin - Patologicheskaia fiziologiia i eksperimental …, 2013 - europepmc.org
In this adiponectin-focused review, the pathophysiological role and the potential therapeutic
benefits of adiponectin in metabolic syndrome (MetS) are analysed. MetS is recognized as …

Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Adiponectin: a new link between obesity, insulin resistance and cardiovascular disease

X Palomer, A Pérez, F Blanco-Vaca - Medicina clinica, 2005 - europepmc.org
Adiponectin is a novel and important member of the adipocytokine family which has
regulatory functions in the glucose and lipid metabolism. Adiponectin stimulates fatty acids …

[图书][B] Adipokines

VR Preedy, RJ Hunter - 2011 - api.taylorfrancis.com
The adipokines (also called adipocytokines), are a group of peptides secreted by adipose
tissue. They have diverse roles, from the cell to the whole body. For example they have …

Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease

Y Matsuzawa - Nature clinical practice Cardiovascular medicine, 2006 - nature.com
Abdominal fat accumulation has been shown to play crucial roles in the development of
metabolic syndrome. Visceral fat accumulation particularly is closely correlated to the …

Adiponectin and cardiovascular risk. From pathophysiology to clinic: focus on children and adolescents

A Orlando, E Nava, M Giussani, S Genovesi - International journal of …, 2019 - mdpi.com
Adiponectin (Ad) is a cytokine produced by adipocytes that acts on specific receptors of
several tissues through autocrine, paracrine, and endocrine signaling mechanisms. Ad is …

Adiponectin as a routine clinical biomarker

K Kishida, T Funahashi, I Shimomura - Best practice & research Clinical …, 2014 - Elsevier
Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the
peripheral blood. However, circulating adiponectin level is inversely related with body …

Possible new therapeutic approach for obesity‐related diseases: Role of adiponectin receptor agonists

CH Lee, YJ Hung - Journal of diabetes investigation, 2015 - Wiley Online Library
Adiponectin is a major adipokine that seems to have a crucial role in the protection from
many metabolic abnormalities. There have been several reports that suggest a strong …

[HTML][HTML] Novel adipokines: their potential role in the pathogenesis of obesity and metabolic disorders

E Korek, H Krauss - Advances in Hygiene and Experimental Medicine, 2015 - phmd.pl
Since identification in 1994 of leptin, a hormone produced by adipocytes, adipose tissue has
become the subject of intensive research. These studies contributed to the discovery that …

Adiponectin: A mediator of obesity, insulin resistance, diabetes, and the metabolic syndrome

M Sharma, JA McClung, NG Abraham - Translational Research in Coronary …, 2016 - Elsevier
The worldwide prevalence of obesity has nearly doubled since 1980. More than 42 million
children under the age of 5 years were overweight in 2013 according to the World Health …