Chondroitin sulfate inhibits lipopolysaccharide-induced inflammation in rat astrocytes by preventing nuclear factor kappa B activation
N Cañas, R Gorina, AM Planas, J Vergés, E Montell… - Neuroscience, 2010 - Elsevier
Chondroitin sulfate (CS) is a glucosaminoglycan (GAG) currently used for the treatment of
osteoarthritis because of its antiinflammatory and antiapoptotic actions. Recent evidence …
osteoarthritis because of its antiinflammatory and antiapoptotic actions. Recent evidence …
A sulfated disaccharide derived from chondroitin sulfate proteoglycan protects against inflammation‐associated neurodegeneration
A Rolls, L Cahalon, S Bakalash, H Avidan… - The FASEB …, 2006 - Wiley Online Library
Chondroitin sulfate proteoglycan (CSPG), a matrix protein that occurs naturally in the central
nervous system (CNS), is considered to be a major inhibitor of axonal regeneration and is …
nervous system (CNS), is considered to be a major inhibitor of axonal regeneration and is …
Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells
SB Jeon, HJ Yoon, SH Park, IH Kim… - The Journal of …, 2008 - journals.aai.org
Sulfatide, a major lipid component of myelin sheath, participates in diverse cellular events of
the CNS, and its cellular level has recently been implicated in many inflammation …
the CNS, and its cellular level has recently been implicated in many inflammation …
[HTML][HTML] Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans
The antiinflammatory and antiapoptotic effects of chondroitin sulfate (CS) are being used to
treat osteoarthritis. Recent evidence has revealed that those peripheral effects of CS may …
treat osteoarthritis. Recent evidence has revealed that those peripheral effects of CS may …
NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia
Activation of microglial cells, the resident immune cells of the CNS causes neurotoxicity
through the release of a wide array of inflammatory mediators including proinflammatory …
through the release of a wide array of inflammatory mediators including proinflammatory …
Inhibitory effect of sesaminol glucosides on lipopolysaccharide-induced NF-κB activation and target gene expression in cultured rat astrocytes
SY Lee, DJ Son, YK Lee, JW Lee, HJ Lee, YW Yun… - Neuroscience …, 2006 - Elsevier
The inflammatory reaction plays an important role in the pathogenesis of the
neurodegenerative disorder including Alzheimer's disease (AD). Sesame lignan compounds …
neurodegenerative disorder including Alzheimer's disease (AD). Sesame lignan compounds …
Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS
MD Martín-de-Saavedra, L del Barrio, N Canas… - Neurochemistry …, 2011 - Elsevier
The glycosaminoglycan chondroitin sulfate (CS) is a major constituent of the extracellular
matrix of the central nervous system where it can constitute part of the perineuronal nets …
matrix of the central nervous system where it can constitute part of the perineuronal nets …
[HTML][HTML] Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases
M Lee, EG McGeer, PL McGeer - Journal of neuroinflammation, 2016 - Springer
Background Sodium thiosulfate (STS) is an industrial chemical which has also been
approved for the treatment of certain rare medical conditions. These include cyanide …
approved for the treatment of certain rare medical conditions. These include cyanide …
Immunomodulatory and anti‐inflammatory effects of chondroitin sulphate
P du Souich, AG García, J Vergés… - Journal of cellular and …, 2009 - Wiley Online Library
Biochemistry of chondrotin sulphate• Mechanism of action of chondroitin sulphate‐Effect of
chondroitin sulphate on the chondrocyte‐Effect of chondroitin sulphate on the synovial …
chondroitin sulphate on the chondrocyte‐Effect of chondroitin sulphate on the synovial …
[HTML][HTML] Inhibitor of hyaluronic acid synthesis 4-methylumbelliferone as an anti-inflammatory modulator of lps-mediated astrocyte responses
DV Chistyakov, AI Nikolskaya, SV Goriainov… - International Journal of …, 2020 - mdpi.com
Astrocytes are glial cells that play an important role in neuroinflammation. Astrocytes
respond to many pro-inflammatory stimuli, including lipopolysaccharide (LPS), an agonist of …
respond to many pro-inflammatory stimuli, including lipopolysaccharide (LPS), an agonist of …