Pro-inflammatory factors released by activated microglia may contribute to the progression
of neurodegenerative diseases. As a natural phenolic acid, chlorogenic acid (CGA) has …

Background Neuroinflammatory processes are considered a double-edged sword, having
both protective and detrimental effects in the brain. Microglia, the brain's resident innate …

The neurotoxicity of aggregated amyloid β (Aβ) has been implicated as a critical cause in the
pathogenesis of Alzheimer's disease. In a previous work, we have shown that low-molecular …

Background Chondroitin sulfate (CS) is found in humans' cartilage, bone, cornea, skin, and
arterial wall. It consists of the foundation substance in the extracellular matrix (ECM) of …

Background Neurodegenerative disorders are associated with chronic neuroinflammation,
which contributes to their pathogenesis and progression. Resveratrol (RSV) is a …

Alzheimer's disease (AD) is the most prevalent neurogenerative disease, characterized by
progressive memory loss and cognitive deficits. Intracellular neurofibrillary tangles (NFTs) …

Neuroinflammation is closely implicated in the pathogenesis of neurological diseases. The
hallmark of neuroinflammation is the microglia activation. Upon activation, microglia are …

Chondroitin sulfate is referred as a symptomatic slow‐acting drug for osteoarthritis because
it improves articular function, and reduces joint swelling and effusion. In addition, chondroitin …

Neurodegeneration is typically preceded by neuroinflammation generated by the nervous
system to protect itself from tissue damage, however, excess neuroinflammation may …

Chronic consumption of β‐sitosterol‐β‐D‐glucoside (BSSG), a neurotoxin contained in
cycad seeds, leads to Parkinson's disease in humans and rodents. Here, we explored …