Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma

NL Albert, DV Nelwan, DF Fleischmann… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The 18-kDa translocator protein (TSPO) is gaining recognition as a relevant target in
glioblastoma imaging. However, data on the potential prognostic value of TSPO PET …

TSPO PET signal using [18F]GE180 is associated with survival in recurrent gliomas

S Quach, A Holzgreve, L Kaiser, M Unterrainer… - European Journal of …, 2023 - Springer
Purpose Glioma patients, especially recurrent glioma, suffer from a poor prognosis. While
advances to classify glioma on a molecular level improved prognostication at initial …

Prognostic value of 11C-methionine volume-based PET parameters in IDH wild type glioblastoma

BRJ van Dijken, AO Ankrah, GN Stormezand… - Plos one, 2022 - journals.plos.org
Purpose 11C-Methionine (11C-MET) PET prognostication of isocitrate dehydrogenase (IDH)
wild type glioblastomas is inadequate as conventional parameters such as standardized …

Prognostic value of pre-irradiation FET PET in patients with not completely resectable IDH-wildtype glioma and minimal or absent contrast enhancement

J Rosen, G Stoffels, P Lohmann, EK Bauer… - Scientific reports, 2021 - nature.com
In glioma patients, complete resection of the contrast-enhancing portion is associated with
improved survival, which, however, cannot be achieved in a considerable number of …

Combination of pre-treatment dynamic [18F]FET PET radiomics and conventional clinical parameters for the survival stratification in patients with IDH-wildtype …

Z Li, A Holzgreve, LM Unterrainer, VC Ruf… - European Journal of …, 2023 - Springer
Purpose The aim of this study was to build and evaluate a prediction model which
incorporates clinical parameters and radiomic features extracted from static as well as …

TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study

M Unterrainer, DF Fleischmann, F Vettermann… - European journal of …, 2020 - Springer
Background The 18-kDa translocator protein (TSPO) is overexpressed in brain tumours and
represents an interesting target for glioma imaging. 18 F-GE-180, a novel TSPO ligand, has …

18F-DOPA uptake does not correlate with IDH mutation status and 1p/19q co-deletion in glioma

F Cicone, L Carideo, C Scaringi, A Arcella… - Annals of nuclear …, 2019 - Springer
Objective The role of amino acid positron emission tomography (PET) in glioma grading and
outcome prognostication has not yet been well established. This is particularly true in the …

Prediction of survival in patients with IDH-wildtype astrocytic gliomas using dynamic O-(2-[18F]-fluoroethyl)-l-tyrosine PET

EK Bauer, G Stoffels, T Blau, G Reifenberger… - European journal of …, 2020 - Springer
Purpose Integrated histomolecular diagnostics of gliomas according to the World Health
Organization (WHO) classification of 2016 has refined diagnostic accuracy and prediction of …

Role of traditional CHO PET parameters in distinguishing IDH, TERT and MGMT alterations in primary diffuse gliomas

Z Kong, Y Zhang, D Liu, P Liu, Y Shi, Y Wang… - Annals of Nuclear …, 2021 - Springer
Objective Isocitrate dehydrogenase (IDH) mutation, telomerase reverse transcriptase (TERT)
promoter mutation and O 6-methylguanine-DNA methyltransferase (MGMT) promoter …

Maximum 11C-methionine PET uptake as a prognostic imaging biomarker for newly diagnosed and untreated astrocytic glioma

K Nakajo, T Uda, T Kawashima, Y Terakawa… - Scientific Reports, 2022 - nature.com
This study aimed whether the uptake of amino tracer positron emission tomography (PET)
can be used as an additional imaging biomarker to estimate the prognosis of glioma …