[HTML][HTML] MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1
S Ma, A Zhang, X Li, S Zhang, S Liu, H Zhao… - Arthritis research & …, 2020 - Springer
Background Due to the lack of research on the pathological mechanism of
temporomandibular joint osteoarthritis (TMJOA), there are few effective treatment measures …
temporomandibular joint osteoarthritis (TMJOA), there are few effective treatment measures …
[HTML][HTML] Knockdown of exosome‑mediated lnc‑PVT1 alleviates lipopolysaccharide‑induced osteoarthritis progression by mediating the HMGB1/TLR4/NF‑κB pathway …
Y Meng, S Qiu, L Sun, J Zuo - Molecular medicine …, 2020 - spandidos-publications.com
Osteoarthritis is a chronic degenerative joint disease. Long non‑coding RNA plasmacytoma
variant translocation 1 (PVT1) is involved in the progression of osteoarthritis and exosomes …
variant translocation 1 (PVT1) is involved in the progression of osteoarthritis and exosomes …
Interleukin-17 signal transduction pathways implicated in inducing matrix metalloproteinase-3,-13 and aggrecanase-1 genes in articular chondrocytes
J Sylvester, A Liacini, WQ Li, M Zafarullah - Cellular signalling, 2004 - Elsevier
Interleukin (IL)-17 promotes cartilage breakdown by inducing matrix metalloproteinases
(MMPs) and aggrecanases (a disintegrin and metalloproteinase with thrombospondin motif …
(MMPs) and aggrecanases (a disintegrin and metalloproteinase with thrombospondin motif …
MicroRNA-142-3p inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting HMGB1
X Wang, Y Guo, C Wang, H Yu, X Yu, H Yu - Inflammation, 2016 - Springer
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and joint inflammation in which microRNAs are significantly involved. Previous …
degradation and joint inflammation in which microRNAs are significantly involved. Previous …
[HTML][HTML] Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes
L Dai, X Zhang, X Hu, C Zhou, Y Ao - Arthritis research & therapy, 2012 - Springer
Introduction Extracellular matrix (ECM) degradation leads to malfunction of the cartilage in
osteoarthritis (OA). Inflammatory cytokine interleukin-1 beta (IL-1β) functions in ECM …
osteoarthritis (OA). Inflammatory cytokine interleukin-1 beta (IL-1β) functions in ECM …
[HTML][HTML] MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
F Kostopoulou, KN Malizos, I Papathanasiou… - Arthritis research & …, 2015 - Springer
Introduction Several studies have shown that osteoarthritis (OA) is strongly associated with
metabolism-related disorders, highlighting OA as the fifth component of the metabolic …
metabolism-related disorders, highlighting OA as the fifth component of the metabolic …
MicroRNA‐34a‐5p promotes joint destruction during osteoarthritis
H Endisha, P Datta, A Sharma… - Arthritis & …, 2021 - Wiley Online Library
Objective MicroRNA‐34a‐5p (miR‐34a‐5p) expression is elevated in the synovial fluid of
patients with late‐stage knee osteoarthritis (OA); however, its exact role and therapeutic …
patients with late‐stage knee osteoarthritis (OA); however, its exact role and therapeutic …
MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3
L Zhang, J Qiu, J Shi, S Liu, H Zou - Bioengineered, 2021 - Taylor & Francis
Osteoarthritis (OA) is a degenerative joint disease. Dysregulated microRNA (miRNA)
expressions are implicated in OA progression. Consequently, the current study set out to …
expressions are implicated in OA progression. Consequently, the current study set out to …
Long non-coding RNA PVT1, a molecular sponge for miR-149, contributes aberrant metabolic dysfunction and inflammation in IL-1β-simulated osteoarthritic …
Y Zhao, J Zhao, X Guo, J She, Y Liu - Bioscience reports, 2018 - portlandpress.com
Osteoarthritis (OA), a common form of degenerative joint disease, is typified by inflammatory
response and the loss of cartilage matrix. Long non-coding RNAs (lncRNAs) are emerging …
response and the loss of cartilage matrix. Long non-coding RNAs (lncRNAs) are emerging …
[HTML][HTML] m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis
J Yang, M Zhang, D Yang, Y Ma, Y Tang… - … & molecular medicine, 2021 - nature.com
Long noncoding RNAs (lncRNAs) have emerged as important regulators of osteoarthritis
(OA), but the biological roles and clinical significance of most lncRNAs in OA are not fully …
(OA), but the biological roles and clinical significance of most lncRNAs in OA are not fully …