Periodontitis is a collection of chronic inflammatory diseases that are caused by specific
bacteria. The bacteria activate inflammatory mechanisms in the periodontal tissues that …

Although specific bacteria, dental plaque, and age are associated with periodontal disease,
there are currently no reliable predictors of periodontitis severity. Studies in twins have …

Background: Periodontitis is a bacterial disease modified by multiple risk factors. The pro‐
inflammatory cytokine interleukin‐1 (IL‐1) is a key regulator of the host responses to …

Aim: To review the association between genetic variability and the inflammatory response
induced by periodontal infection. Material and Methods: A search of MEDLINE‐PubMed was …

Periodontitis is considered to be a multifactorial disease. Studies have indicated that part of
the clinical variability in periodontitis may be explained by genetic factors. Genes can affect …

Background, aims: Early onset periodontal diseases (EOP) are a group of inflammatory
disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals …

Aim: We conducted a systematic review and a meta‐analysis, in order to investigate the
potential association of cytokine gene polymorphisms with either aggressive or chronic …

An association has been reported between polymorphisms in the genes encoding IL‐1α (−
889) and IL‐1β (+ 3953)(periodontitis susceptibility trait, PST), and an increased severity of …

Background: Genetic polymorphisms at interleukin (IL)‐1α and IL‐1β were recently
suggested to be associated with severity of adult periodontitis. We evaluated whether these …

Background: Interleukin‐1 (IL‐1) gene polymorphisms have been associated with increased
levels of inflammatory mediators and several inflammatory diseases. Periodontitis is a …