[HTML][HTML] Hydrogen sulfide exerts anti-oxidative and anti-inflammatory effects in acute lung injury

KK Zimmermann, SG Spassov, KM Strosing, PM Ihle… - Inflammation, 2018 - Springer
Acute lung injury (ALI) caused by septic stimuli is still a major problem in critical care
patients. We have shown previously that hydrogen sulfide (H 2 S) mediates anti …

[HTML][HTML] Inhaled hydrogen sulfide protects against lipopolysaccharide-induced acute lung injury in mice

S Faller, KK Zimmermann, KM Strosing… - Medical gas …, 2012 - Springer
Background Local pulmonary and systemic infections can lead to acute lung injury (ALI).
The resulting lung damage can evoke lung failure and multiple organ dysfunction …

[HTML][HTML] Pre-and posttreatment with hydrogen sulfide prevents ventilator-induced lung injury by limiting inflammation and oxidation

S Faller, R Seiler, R Donus, H Engelstaedter… - PLoS …, 2017 - journals.plos.org
Although essential in critical care medicine, mechanical ventilation often results in ventilator-
induced lung injury. Low concentrations of hydrogen sulfide have been proven to have anti …

Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation

A Esechie, L Kiss, G Olah, EM Horváth… - Clinical …, 2008 - portlandpress.com
Acute lung injury results in a severe inflammatory response, which leads to priming and
activation of leucocytes, release of reactive oxygen and reactive nitrogen species …

Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice

K Tokuda, K Kida, E Marutani, E Crimi… - Antioxidants & redox …, 2012 - liebertpub.com
Aims: The role of hydrogen sulfide (H2S) in endotoxin (lipopolysaccharide [LPS])-induced
inflammation is incompletely understood. We examined the impact of H2S breathing on LPS …

[HTML][HTML] H2S attenuates LPS-induced acute lung injury by reducing oxidative/nitrative stress and inflammation

HX Zhang, SJ Liu, XL Tang, GL Duan, X Ni… - Cellular Physiology and …, 2016 - karger.com
Background: Hydrogen sulfide (H 2 S), known as the third endogenous gaseous transmitter,
has received increasing attention because of its diverse effects, including angiogenesis …

Regulatory effects of hydrogen sulfide on IL-6, IL-8 and IL-10 levels in the plasma and pulmonary tissue of rats with acute lung injury

T Li, B Zhao, C Wang, H Wang, Z Liu… - Experimental …, 2008 - journals.sagepub.com
We examined the possible role of hydrogen sulfide (H2S) in the pathogenesis of oleic acid
(OA)-induced acute lung injury (ALI) and its regulatory effects on the inflammatory response …

Hydrogen sulfide prevents formation of reactive oxygen species through PI3K/Akt signaling and limits ventilator‐Induced lung injury

SG Spassov, R Donus, PM Ihle… - Oxidative medicine …, 2017 - Wiley Online Library
The development of ventilator‐induced lung injury (VILI) is still a major problem in
mechanically ventilated patients. Low dose inhalation of hydrogen sulfide (H2S) during …

Hydrogen sulfide protects rat lung from ischemia–reperfusion injury

Z Fu, X Liu, B Geng, L Fang, C Tang - Life sciences, 2008 - Elsevier
Recent studies have indicated that hydrogen sulfide (H2S) is capable of modulating many
physiological processes, which prompted us to investigate the potential of H2S as a lung …

[HTML][HTML] Sodium hydrosulfide alleviates lung inflammation and cell apoptosis following resuscitated hemorrhagic shock in rats

D Xu, C Gao, W Niu, Y Li, Y Wang, C Gao… - Acta Pharmacologica …, 2013 - nature.com
Aim: To investigate the protective effects of hydrogen sulfide (H 2 S) against inflammation,
oxidative stress and apoptosis in a rat model of resuscitated hemorrhagic shock. Methods …