[PDF][PDF] The Applications of Genome Editing in the Management of Cancer: A Narrative Overview

II Al-Janabi - Al-Rafidain Journal of Medical Sciences (ISSN 2789 …, 2024 - iasj.net
Objective: To provide an overview of the status of applying genome editing, particularly
CRISPR/Cas9, in the management of cancer. Method: Several search tools were consulted …

[PDF][PDF] A new era of gene editing for the treatment of human diseases

KC Mandip, CJ Steer - Swiss medical weekly, 2019 - smw.ch
The treatment of human diseases using gene-editing technology has been envisioned for
several decades with the realisation that so many were associated with mutations in DNA …

[PDF][PDF] A review on genome editing by CRISPR-CAS9 technique for cancer treatment

MNM Khan, KK Islam, A Ashraf, NC Barman - World Cancer Res J, 2020 - wcrj.net
In this review, we summarize CRISPR-Cas9 system-based gene modification for the
therapeutic treatment of cancer. Cancer is a group of diseases involving anomalous cell …

[HTML][HTML] Genome editing in cancer: Challenges and potential opportunities

D Breier, D Peer - Bioactive Materials, 2023 - Elsevier
Ever since its mechanism was discovered back in 2012, the CRISPR/Cas9 system have
revolutionized the field of genome editing. While at first it was seen as a therapeutic tool …

CRISPR-Cas9: A multifaceted therapeutic strategy for cancer treatment

I Kaushik, S Ramachandran, SK Srivastava - Seminars in cell & …, 2019 - Elsevier
CRISPR-Cas9 is an RNA guided endonuclease that has revolutionized the ability to edit
genome and introduce desired manipulations in the target genomic sequence. It is a flexible …

The applications of CRISPR screen in functional genomics

Guest Editors: Lu Xiao-Jie and Ji Li-Juan… - Briefings in …, 2017 - academic.oup.com
CRISPR technology has rapidly changed the face of biological research, such that precise
genome editing has now become routine for many labs within several years of its initial …

CRISPR: The revolutionary gene editing tool with Far-reaching applications

S Bhattacharyya, A Mukherjee - Biotechnology Business-Concept to …, 2020 - Springer
In the realm of scientific research, there is an immense value for biological research tools,
which can modify, insert, and delete DNA sequences of cells or organisms in order to …

[HTML][HTML] Gene-Editing Tools: Delivery Methods and Challenges

G Palmgren-Jan - crisprmedicinenews.com
Gene-editing systems, especially CRISPR-Cas9, have revolutionised genome editing,
offering potential cures for genetic disorders, cancers, and other diseases. However …

[HTML][HTML] Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine

M Khoshandam, H Soltaninejad, M Mousazadeh… - Genes & …, 2024 - Elsevier
CRISPR/Cas9 is an effective gene editing tool with broad applications for the prevention or
treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced …

Recent Advances and Therapeutic Strategies Using CRISPR Genome Editing Technique for the Treatment of Cancer

S Maity, R Mukherjee, S Banerjee - Molecular Biotechnology, 2023 - Springer
CRISPR genome editing technique has the potential to target cancer cells in a precise
manner. The latest advancements have helped to address one of the prominent concerns …