Today, we have to investigate the effects of selected mutations and molecular alterations-
this is made possible by the new genome editing technologies. In these, either a section of …

The evolution of technology allowed the discovery of the genetic alterations responsible for
various genetic diseases. The treatment options generally available for these pathologies …

Cancer is a genetic disease stemming from genetic and epigenetic mutations and is the
second most common cause of death across the globe. Clustered regularly interspaced …

Genome editing techniques are considered to be one of the most challenging yet efficient
tools for assisting therapeutic approaches. Several studies have focused on the …

CRISPR/Cas9 is an RNA-guided endonuclease that specifically targets a sequence of DNA
by selecting bacteria, archaea enabling an organism to respond to with the utilization of …

CRISPR/Cas9 systems have revolutionised the field of gene editing, allowing for precise
modifications to be generated in vivo to mimic the genetic events found in human cancer …

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer
statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated protein 9 (Cas9)(CRISPR/Cas9) system is a powerful tool that enables precise …

Multitude of gene-altering capabilities in combination with ease of design and low cost have
all led to the adoption of the sophisticated and yet simple gene editing system that are …

The field of molecular biology has been transformed by the development of CRISPR/Cas9
gene editing technology, which has opened up previously unimaginable possibilities for the …