Although the apoptotic cell death process in the prostate is known to be under the control of
androgens, the key components targeted by the hormones remain to be investigated. In the …

Early in postnatal life the first phase of spermatogenesis is accompanied by an initial wave
of germ cell apoptosis. This wave of germ cell death is thought to reflect an adjustment of …

Testosterone promotes apoptotic damage in human renal tubular cells. Background
Apoptosis is a mode of cell death that participates in the kidney physiologic remodeling …

Apoptosis is an integral part of the spermatogenic process, necessary to maintain a proper
ratio of Sertoli to germ cell numbers and provide an adequate microenvironment to germ …

The necessity of estrogens for male fertility was recently discovered in studies on both
estrogen receptor α knockout and aromatase (cyp 19 gene) knockout mice. However, direct …

Contents As the exact role for exogenous oestrogen in spermatogenesis is not fully
understood, the aim of this study was to investigate the effect of estradiol benzoate (EB) …

Aims: Many men endure immunosuppressive or anticancer treatments that contain alkylating
agents before the age of sexual maturity, especially the increasing number of preadolescent …

Onset of spermatogenesis is associated with an apoptosis wave that limits its efficiency
during the first cycles in most mammals. Beyond the first cycles the actual efficiency of …

In the present study an in vitro model was developed and characterized for evaluation of the
role of apoptosis in adult human testes. The samples came from adult men undergoing …

Several processes including oxidative stress, apoptosis, inflammation and autophagy are
related to testicular function. Recent studies indicate that a crosstalk between apoptosis and …