Serum thyroxine (T4), triiodothyronine (T3), resin uptake of T3 (RT3U), thyroid stimulating
hormone (TSH) and TSH response to thyrotropin releasing hormone (TRH) were measured …

The effects of amiodarone on thyroid function tests in 100 patients treated for 6 weeks to 8
years are reported. One patient became thyrotoxic and 10 developed latent or overt …

2-n-Butyl-3-(4'-diethylaminoethoxy-3', 5'-diiodobenzoyl)-benzofurane (amiodarone), a drug
used in arrythmias and angina pectoris, contains 75 mg of organic iodine/200 mg active …

Thyroid function alterations induced by amiodarone treatment (200-400 mg/day for 5
days/week) were studied in 50 patients with heart disease (age 34-75 years, mean age …

Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone, an iodinated benzofuran derivative, was introduced in the 1960s as an
antianginal agent with coronary vasodilator properties. Later description of its antiaiThythmic …

Amiodarone was given by daily intraperitoneal injection (10 mg/kg body weight) to a group
of 11 New Zealand white rabbits. Over 6 weeks there were significant increases (P< 0–01) in …

Of a population of 400 patients treated with amiodarone, 97 underwent thyroid function
evaluation. Of these, 20 patients proved to be thyrotoxic and 16 hypothyroid. In thyrotoxic …

Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Pituitary-thyroid function was tested in 15 euthyroid patients before, during, and after long
term oral treatment with amiodarone (2-n-butyl-3, 4′-diethylaminoethoxy-3′, 5 …