IRT1 DEGRADATION FACTOR1, a RING E3 Ubiquitin Ligase, Regulates the Degradation of IRON-REGULATED TRANSPORTER1 in Arabidopsis

LJ Shin, JC Lo, GH Chen, J Callis, H Fu… - The Plant Cell, 2013 - academic.oup.com
Fe is an essential micronutrient for plant growth and development; plants have developed
sophisticated strategies to acquire ferric Fe from the soil. Nongraminaceous plants acquire …

Dynamic control of the high-affinity iron uptake complex in root epidermal cells

A Martín-Barranco, J Spielmann, G Dubeaux… - Plant …, 2020 - academic.oup.com
In plants, iron uptake from the soil is tightly regulated to ensure optimal growth and
development. Iron absorption in Arabidopsis root epidermal cells requires the IRT1 …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

Arabidopsis IRT2 cooperates with the high-affinity iron uptake system to maintain iron homeostasis in root epidermal cells

G Vert, M Barberon, E Zelazny, M Séguéla, JF Briat… - Planta, 2009 - Springer
Iron is an essential nutrient for all organisms but toxic when present in excess.
Consequently, plants carefully regulate their iron uptake, dependent on the FRO2 ferric …

[HTML][HTML] Metal sensing by the IRT1 transporter-receptor orchestrates its own degradation and plant metal nutrition

G Dubeaux, J Neveu, E Zelazny, G Vert - Molecular cell, 2018 - cell.com
Plant roots forage the soil for iron, the concentration of which can be dramatically lower than
those needed for growth. Soil iron uptake uses the broad metal spectrum IRT1 transporter …

Root‐to‐shoot iron partitioning in Arabidopsis requires IRON‐REGULATED TRANSPORTER1 (IRT1) protein but not its iron (II) transport function

J Quintana, M Bernal, M Scholle… - The Plant …, 2022 - Wiley Online Library
SUMMARY IRON‐REGULATED TRANSPORTER1 (IRT1) is the root high‐affinity ferrous
iron (Fe) uptake system and indispensable for the completion of the life cycle of Arabidopsis …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Hormone influence on the spatial regulation of IRT1 expression in iron-deficient Arabidopsis thaliana roots

A Blum, T Brumbarova, P Bauer… - Plant signaling & …, 2014 - Taylor & Francis
The IRON-REGULATED TRANSPORTER1 (IRT1) is the principal importer of soil iron in
Arabidopsis thaliana. It has a complex intracellular trafficking behavior, including continuous …

The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI

SA Kim, IS LaCroix, SA Gerber… - Proceedings of the …, 2019 - National Acad Sciences
Iron is an essential nutrient for plants, but excess iron is toxic due to its catalytic role in the
formation of hydroxyl radicals. Thus, iron uptake is highly regulated and induced only under …