Metabolomics by gas chromatography–mass spectrometry: Combined targeted and untargeted profiling
O Fiehn - Current protocols in molecular biology, 2016 - Wiley Online Library
Gas chromatography–mass spectrometry (GC‐MS)–based metabolomics is ideal for
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …
Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry
O Fiehn - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
Gas chromatography coupled to mass spectrometry (GC-MS) is one of the most frequently
used tools for profiling primary metabolites. Instruments are mature enough to run large …
used tools for profiling primary metabolites. Instruments are mature enough to run large …
Untargeted GC-MS Metabolomics
MEP Papadimitropoulos, CG Vasilopoulou… - … profiling: Methods and …, 2018 - Springer
Untargeted metabolomics refers to the high-throughput analysis of the metabolic state of a
biological system (eg, tissue, biological fluid, cell culture) based on the concentration profile …
biological system (eg, tissue, biological fluid, cell culture) based on the concentration profile …
metaMS: An open-source pipeline for GC–MS-based untargeted metabolomics
Untargeted metabolomics are rapidly becoming an important tool for studying complex
biological samples. Gas chromatography–mass spectrometry (GC–MS) is the most widely …
biological samples. Gas chromatography–mass spectrometry (GC–MS) is the most widely …
Gas chromatography-mass spectrometry (GC-MS)-based metabolomics
Metabolic fingerprinting, the main tool in metabolomics, is a non-targeted methodology
where all detectable peaks (or signals), including those from unknown analytes, are …
where all detectable peaks (or signals), including those from unknown analytes, are …
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
[HTML][HTML] GC–MS libraries for the rapid identification of metabolites in complex biological samples
N Schauer, D Steinhauser, S Strelkov, D Schomburg… - FEBS letters, 2005 - Elsevier
Gas chromatography–mass spectrometry based metabolite profiling of biological samples is
rapidly becoming one of the cornerstones of functional genomics and systems biology. Thus …
rapidly becoming one of the cornerstones of functional genomics and systems biology. Thus …
Practical non-targeted gas chromatography/mass spectrometry-based metabolomics platform for metabolic phenotype analysis
H Tsugawa, T Bamba, M Shinohara, S Nishiumi… - Journal of bioscience …, 2011 - Elsevier
Gas chromatography coupled to mass spectrometry (GC/MS) is a core analytical method for
metabolomics and has been used as a platform in non-targeted analysis, especially for …
metabolomics and has been used as a platform in non-targeted analysis, especially for …
Review of recent developments in GC–MS approaches to metabolomics-based research
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …
biological systems in response to intrinsic and extrinsic factors. This is accomplished …
Systematic identification of conserved metabolites in GC/MS data for metabolomics and biomarker discovery
MP Styczynski, JF Moxley, LV Tong, JL Walther… - Analytical …, 2007 - ACS Publications
Analysis of metabolomic profiling data from gas chromatography− mass spectrometry
(GC/MS) measurements usually relies upon reference libraries of metabolite mass spectra to …
(GC/MS) measurements usually relies upon reference libraries of metabolite mass spectra to …