Behavioral indications for serotonin receptor hypersensitivity in panic disorder
RS Kahn, S Wetzler, HM Van Praag, GM Asnis… - Psychiatry …, 1988 - Elsevier
Immediate placebo-corrected behavioral responses to m-chlorophenylpiperazine (MCPP), a
selective serotonin agonist, are reported in 11 normal controls, 10 patients with panic …
selective serotonin agonist, are reported in 11 normal controls, 10 patients with panic …
Long-term administration of citalopram reduces basal and stress-induced extracellular noradrenaline levels in rat brain
Y Kawahara, H Kawahara, F Kaneko, M Tanaka - Psychopharmacology, 2007 - Springer
Rationale Panic disorders are commonly treated with selective serotonin reuptake inhibitors
(SSRIs). However, the effect of SSRIs on noradrenaline systems in the brain has not been …
(SSRIs). However, the effect of SSRIs on noradrenaline systems in the brain has not been …
Panic disorder: the potential role of serotonin reuptake inhibitors.
DV Sheehan, JP Zak, JA Miller Jr… - The Journal of Clinical …, 1988 - europepmc.org
The authors review the role of the serotonergic system in panic disorder and the potential for
use of the new serotonin (5-HT) reuptake inhibitors in treating panic disorder. Data currently …
use of the new serotonin (5-HT) reuptake inhibitors in treating panic disorder. Data currently …
Acute and chronic effects of selective serotonin reuptake inhibitor treatment on fear conditioning: implications for underlying fear circuits
NS Burghardt, EP Bauer - Neuroscience, 2013 - Elsevier
Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of a
spectrum of anxiety disorders, yet paradoxically they may increase symptoms of anxiety …
spectrum of anxiety disorders, yet paradoxically they may increase symptoms of anxiety …
R-citalopram counteracts the effect of escitalopram in a rat conditioned fear stress model of anxiety
S-citalopram (escitalopram) mediates the serotonin reuptake inhibitory effect of the
racemate, R, S-citalopram. The effect of escitalopram (0.5–3.9 mg/kg) was investigated in a …
racemate, R, S-citalopram. The effect of escitalopram (0.5–3.9 mg/kg) was investigated in a …
The role of serotonin in depression and anxiety
JFW Deakin - European Psychiatry, 1998 - cambridge.org
The different coping responses to three types of aversive events-future threats, acute events
and chronic stress—may be modulated by 5HT projections. Dysfunction in these coping …
and chronic stress—may be modulated by 5HT projections. Dysfunction in these coping …
Serotonin mechanisms in animal models of anxiety.
SL Handley, JW McBlane - Brazilian Journal of Medical and …, 1993 - europepmc.org
1. Responses to serotonergic drugs in animal models of anxiety are reviewed. Pre-and
postsynaptic mechanisms and multiple sites of postsynaptic action contribute to conflicting …
postsynaptic mechanisms and multiple sites of postsynaptic action contribute to conflicting …
Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: a randomized placebo controlled trial of yohimbine augmentation
Preliminary animal research suggests that yohimbine hydrochloride, a selective competitive
alpha2-adrenergic receptor antagonist, accelerates fear extinction and converts ineffective …
alpha2-adrenergic receptor antagonist, accelerates fear extinction and converts ineffective …