[HTML][HTML] Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family

B Ochoa-Lizarralde, YG Gao, AN Popov… - Journal of Biological …, 2018 - ASBMB
The glycolipid transfer protein (GLTP) fold defines a superfamily of eukaryotic proteins that
selectively transport sphingolipids (SLs) between membranes. However, the mechanisms …

Sphingolipid transfer proteins defined by the GLTP-fold

L Malinina, DK Simanshu, X Zhai… - Quarterly reviews of …, 2015 - cambridge.org
Glycolipid transfer proteins (GLTPs) originally were identified as small (~ 24 kDa), soluble,
amphitropic proteins that specifically accelerate the intermembrane transfer of glycolipids …

[HTML][HTML] The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure

L Malinina, ML Malakhova, AT Kanack, M Lu… - PLoS …, 2006 - journals.plos.org
Glycosphingolipids (GSLs) play major roles in cellular growth and development. Mammalian
glycolipid transfer proteins (GLTPs) are potential regulators of cell processes mediated by …

The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral …

RK Kamlekar, DK Simanshu, Y Gao, R Kenoth… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Phosphoinositol 4-phosphate adaptor protein-2 (FAPP2) plays a key role in
glycosphingolipid (GSL) production using its C-terminal domain to transport newly …

[HTML][HTML] Human glycolipid transfer protein (GLTP) expression modulates cell shape

Y Gao, T Chung, X Zou, HM Pike, RE Brown - PLoS One, 2011 - journals.plos.org
Glycolipid transfer protein (GLTP) accelerates glycosphingolipid (GSL) intermembrane
transfer via a unique lipid transfer/binding fold (GLTP-fold) that defines the GLTP superfamily …

[HTML][HTML] Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide

X Zou, Y Gao, VR Ruvolo, TL Gardner… - Journal of Biological …, 2011 - ASBMB
Glycolipid transfer protein (GLTP) accelerates glycolipid intermembrane transfer via a
unique lipid transfer/binding fold (GLTP fold) that defines the GLTP superfamily and is the …

Glycolipid transfer proteins

RE Brown, P Mattjus - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2007 - Elsevier
Glycolipid transfer proteins (GLTPs) are small (24 kDa), soluble, ubiquitous proteins
characterized by their ability to accelerate the intermembrane transfer of glycolipids in vitro …

[HTML][HTML] Ceramide-1-phosphate transfer protein promotes sphingolipid reorientation needed for binding during membrane interaction

YG Gao, J McDonald, L Malinina, DJ Patel… - Journal of lipid …, 2022 - ASBMB
Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with
source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) …

Specificity of the mammalian glycolipid transfer proteins

P Mattjus - Chemistry and physics of lipids, 2016 - Elsevier
Structurally the glycolipid transfer protein (GLTP) fold differs from other proteins that
recognize glycolipids, such as non-specific lipid transfer proteins and lysosomal lipid …

[HTML][HTML] Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome

MA Kjellberg, APE Backman, H Ohvo-Rekilä… - PLoS One, 2014 - journals.plos.org
The glycolipid transfer protein (GLTP) catalyzes the binding and transport of glycolipids, but
not phospholipids or neutral lipids. With its all-alpha helical fold, it is the founding member …