The effect of deformability on the microscale flow behavior of red blood cell suspensions

A Passos, JM Sherwood, E Kaliviotis, R Agrawal… - Physics of …, 2019 - pubs.aip.org
Red blood cell (RBC) deformability is important for tissue perfusion and a key determinant of
blood rheology. Diseases such as diabetes, sickle cell anemia, and malaria, as well as …

Importance of viscosity contrast for the motion of erythrocytes in microcapillaries

AK Dasanna, J Mauer, G Gompper, DA Fedosov - Frontiers in Physics, 2021 - frontiersin.org
The dynamics and deformation of red blood cells (RBCs) in microcirculation affect the flow
resistance and transport properties of whole blood. One of the key properties that can alter …

High-throughput microfluidic characterization of erythrocyte shapes and mechanical variability

F Reichel, J Mauer, AA Nawaz, G Gompper, J Guck… - Biophysical journal, 2019 - cell.com
The motion of red blood cells (RBCs) in microchannels is important for microvascular blood
flow and biomedical applications such as blood analysis in microfluidics. The current …

Red blood cell aggregates and their effect on non-Newtonian blood viscosity at low hematocrit in a two-fluid low shear rate microfluidic system

R Mehri, C Mavriplis, M Fenech - Plos one, 2018 - journals.plos.org
Red blood cells (RBCs) are the most abundant cells in human blood. Remarkably RBCs
deform and bridge together to form aggregates under very low shear rates. The theory and …

Effect of cytosol viscosity on the flow behavior of red blood cell suspensions in microvessels

W Chien, G Gompper, DA Fedosov - Microcirculation, 2021 - Wiley Online Library
Objective The flow behavior of blood is strongly affected by red blood cell (RBC) properties,
such as the viscosity ratio C between cytosol and suspending medium, which can …

Inertia-dependent dynamics of three-dimensional vesicles and red blood cells in shear flow

ZY Luo, SQ Wang, L He, F Xu, BF Bai - Soft Matter, 2013 - pubs.rsc.org
A three-dimensional (3D) simulation study of the effect of inertia on the dynamics of vesicles
and red blood cells (RBCs) has not been reported. Here, we developed a 3D model based …

Microconfined flow behavior of red blood cells

G Tomaiuolo, L Lanotte, R D'Apolito… - Medical engineering & …, 2016 - Elsevier
Red blood cells (RBCs) perform essential functions in human body, such as gas exchange
between blood and tissues, thanks to their ability to deform and flow in the microvascular …

Red blood cell deformation in microconfined flow

G Tomaiuolo, M Simeone, V Martinelli, B Rotoli… - Soft Matter, 2009 - pubs.rsc.org
In this work, we report on a systematic fluidodynamic investigation of red blood cell (RBC)
suspensions flowing in microcapillaries with diameters comparable to the cell size in vitro …

Effects of red blood cell aggregation on the blood flow in a symmetrical stenosed microvessel

LL Xiao, CS Lin, S Chen, Y Liu, BM Fu… - … and modeling in …, 2020 - Springer
In order to figure out whether red blood cell (RBC) aggregation is beneficial or deleterious
for the blood flow through a stenosis, fluid mechanics of a microvascular stenosis was …

Microconfined flow behavior of red blood cells in vitro

S Guido, G Tomaiuolo - Comptes Rendus Physique, 2009 - Elsevier
The high red blood cell (RBC) deformability is essential to optimal gas exchange between
gas and tissues in microcirculation in vivo. This review is focused on the flow behavior of …