BACKGROUND Second malignant neoplasms have been noted infrequently in survivors of
osteosarcoma treated before 1970. METHODS For the above reason, the authors surveyed …

BACKGROUND The authors investigated the incidence and relative risk of secondary
malignant neoplasms in long‐term survivors of osteosarcoma. METHODS A comprehensive …

We studied the pedigrees of 17 index patients with osteosarcoma, recording malignant
disease and cause of death for first-and second-degree relatives. There were seven cancers …

Osteosarcoma is the most common primary bone sarcoma. Several studies published in the
1960s established that approximately one fifth of patients survive when treated with surgery …

One hundred thirty-five patients younger than 30 years with osteosarcoma were treated at
the Chiba Cancer Center between 1976 and 1999. They included six patients with second …

Purpose: The aim of this study is to compare primary and secondary osteosarcomas using
data from the National Cancer Institute's Surveillance, Epidemiology and End Results …

BACKGROUND The objective of the current study was to determine the incidence, clinical
and pathologic characteristics, and outcome of patients with conventional osteosarcoma …

New oncologic treatments have improved survival in osteosarcoma and Ewing's sarcoma.
However, these treatments may cause secondary malignancies after radiotherapy. This …

PURPOSE: The prognosis of osteosarcoma occurring as a second malignant disease (OS-
SMD) is thought to be poor. We attempted to evaluate whether this holds true when OS-SMD …

Background. The purpose of this work was to study clinical and histopathological tumor
characteristics of patients treated for synchronous or metachronous skeletal osteosarcoma …