Objective: Researchers disagree as to whether irritability is a diagnostic indicator for
pediatric mania in bipolar disorder. The authors compared the behavioral and …

Questions persist regarding the presentation of bipolar disorder (BD) in youth and the
nosological significance of irritability. Of particular interest is whether severe mood …

In recent years, increasing numbers of children have been diagnosed with bipolar disorder.
In some cases, children with unstable mood clearly meet current diagnostic criteria for …

OBJECTIVE: To determine whether some children with bipolar disorder (BP) manifest
irritability without elation and whether these children differ on sociodemographic …

BACKGROUND: We hypothesized that irritability is a heterogeneous symptom distinguished
by severity and that attending to this heterogeneity would impact the relationship between …

We suggest that the core feature of bipolar disorder (BPD) is marked state fluctuations. The
pathophysiology of switches into depressed, irritable, and extreme positive valence states …

OBJECTIVE: Clinicians and researchers debate whether children with chronic, nonepisodic
irritability should receive the diagnosis of bipolar disorder (BD). To address this debate, we …

Background: Irritability is prevalent and impairing in pediatric bipolar disorder (BD) but has
been minimally studied using neuroimaging techniques. We used …

Studying attention in the context of emotional stimuli may aid in differentiating pediatric
bipolar disorder (BD) from severe mood dysregulation (SMD). SMD is characterized by …

Irritability is an important symptom in childhood psychopathology that has received relatively
little research attention. Recent controversy concerning the diagnosis of mania in children …