Estrogens still represent an attractive therapeutic approach for Alzheimer's disease

E Tamagno, M Guglielmotto - Neural Regeneration Research, 2022 - journals.lww.com
Alzheimer's disease (AD) is a progressive neurodegenerative condition that goes from mild
cognitive impairment in prodromal disease to severely disabling deficits in advanced stages …

[PDF][PDF] Estrogens and brain function

A Markou, T Duka, GM Prelevic - Hormones, 2005 - hormones.gr
Cognitive decline is well recognized during ageing but is often accelerated in women after
menopause. Studies have shown that there are significant gender differences in brain …

Can estrogens prevent neurodegeneration?

LS Schneider, CE Finch - Drugs & aging, 1997 - Springer
Estrogen replacement therapy appears to have significant beneficial effects on cognition
and mood in the elderly. In recent studies, its use has been associated with short term …

Impact of estrogen therapy on Alzheimer's disease: a fork in the road?

RD Brinton - CNS drugs, 2004 - Springer
The results of recent clinical studies have challenged our previously held view that estrogen
therapy promotes neurological health and prevents or ameliorates Alzheimer's disease. A …

Can estrogen play a significant role in the prevention of Alzheimer's disease?

JP Kesslak - Ageing and Dementia Current and Future Concepts, 2002 - Springer
In women the abrupt decline estrogen levels at menopause may be associated with
cognitive deficits and increased risk for Alzheimer's disease (AD); estrogen replacement …

[图书][B] The short lived effects of hormone therapy on cognitive function

E Hogervorst - 2006 - books.google.com
Dementia is characterized by severe memory and other cognitive deficits that interfere with
daily life. Alzheimer disease (AD), the most prevalent type of dementia, is characterized by a …

Is hormone replacement therapy a risk factor or a therapeutic option for Alzheimer's disease?

ZB Mills, RLM Faull, A Kwakowsky - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …

Estrogen and Alzheimer's disease: the story so far

B Cholerton, CE Gleason, LD Baker, S Asthana - Drugs & aging, 2002 - Springer
The ovarian hormone estrogen has long been used to treat the physical symptoms of
menopause and to aid in the prevention of osteoporosis in postmenopausal women …

Understanding the role of estrogen on cognition and dementia

M Sano - Advances in Dementia Research, 2000 - Springer
There is growing evidence that post menopausal use of estrogen may have a beneficial
effect on cognition and may reduce the risk of dementia. In a vast majority of studies, the use …

Estrogens: mechanisms of neuroprotective effects

S Petrovska, B Dejanova, V Jurisic - Journal of Physiology and …, 2012 - Springer
Within the last few years, there has been a growing interest in the neuroprotective effects of
estrogen and the possible beneficial effects of estrogen in neurodegenerative diseases such …