Background Right ventricular failure (RVF) is a leading cause of morbidity and mortality in
multiple cardiovascular diseases, but there are no treatments for RVF as therapeutic targets …

Heart failure (HF) patients with deteriorating right ventricular (RV) structure and function
have a nearly twofold increased risk of death compared with those without. Despite the well …

Background Right ventricular (RV) dysfunction contributes to mortality in chronic heart failure
(HF). However, the molecular mechanisms of RV failure remain poorly understood, and RV …

Aim: Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy that
results in death from right ventricular failure (RVF). There is limited understanding of the …

Right ventricular (RV) remodeling comprises multiple adaptation mechanisms to increased
pressure-or volume-overload, which in concert determine RV performance as well as clinical …

The right ventricle (RV) differs in several aspects from the left ventricle (LV) including its
embryonic origin, physiological role and anatomical design. In contrast to LV hypertrophy …

Background: Right ventricular (RV) dysfunction is a significant prognostic determinant of
morbidity and mortality in pulmonary arterial hypertension (PAH). Despite the importance of …

Right ventricular failure (RVF) is the most important prognostic factor for both morbidity and
mortality in pulmonary arterial hypertension (PAH), but also occurs in numerous other …

Right ventricular dysfunction is a hallmark of advanced pulmonary vascular, lung
parenchymal, and left heart disease, yet the underlying mechanisms that govern (mal) …

Right ventricular (RV) failure remains the strongest determinant of survival in pulmonary
hypertension (PH). We aimed to identify relevant mechanisms, beyond pressure overload …