Regulation of ELAV/Hu RNA-binding proteins by phosphorylation

U Bräuer, E Zaharieva, M Soller - Biochemical Society …, 2014 - portlandpress.com
ELAV (embryonic lethal/abnormal visual system)/Hu proteins comprise a family of highly
related neuronal RBPs (RNA-binding proteins) involved in many aspects of mRNA …

Concentration and localization of coexpressed ELAV/Hu proteins control specificity of mRNA processing

E Zaharieva, IU Haussmann, U Bräuer… - Molecular and cellular …, 2015 - Am Soc Microbiol
Neuronally coexpressed ELAV/Hu proteins comprise a family of highly related RNA binding
proteins which bind to very similar cognate sequences. How this redundancy is linked to in …

Regulation of neuronal RNA signatures by ELAV/Hu proteins

V Hilgers - Wiley Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
The RNA‐binding proteins encoded by the highly conserved elav/Hu gene family, found in
all metazoans, regulate the expression of a wide range of genes, at both the co …

Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

W Akamatsu, HJ Okano, N Osumi… - Proceedings of the …, 1999 - National Acad Sciences
Hu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal
RNA-binding proteins that contain three RNA recognition motifs. Although Drosophila ELAV …

Regulation of the ELAV target ewg: insights from an evolutionary perspective

M Soller, M Li, IU Haussmann - 2008 - portlandpress.com
ELAV (embryonic lethal abnormal visual system)/Hu family proteins are prototype RNA-
binding proteins with binding preferences for AU-rich regions. Due to frequent occurrence of …

Neuronal ELAV proteins enhance mRNA stability by a PKCα-dependent pathway

A Pascale, M Amadio, G Scapagnini… - Proceedings of the …, 2005 - National Acad Sciences
More than 1 in 20 human genes bear in the mRNA 3′ UTR a specific motif called the
adenine-and uridine-rich element (ARE), which posttranscriptionally determines its …

ELAV proteins along evolution: back to the nucleus?

C Colombrita, V Silani, A Ratti - Molecular and Cellular Neuroscience, 2013 - Elsevier
The complex interplay of post-transcriptional regulatory mechanisms mediated by RNA-
binding proteins (RBP) at different steps of RNA metabolism is pivotal for the development of …

Shared RNA-binding sites for interacting members of the Drosophila ELAV family of neuronal proteins

CD Borgeson, ML Samson - Nucleic acids research, 2005 - academic.oup.com
The product of the Drosophila embryonic lethal abnormal visual system is a conserved
protein (ELAV) necessary for normal neuronal differentiation and maintenance. It possesses …

[HTML][HTML] RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein

SSY Peng, CYA Chen, N Xu, AB Shyu - The EMBO journal, 1998 - embopress.org
An important paradigm for post‐transcriptional regulation is the control of cytoplasmic mRNA
stability mediated by AU‐rich elements (AREs) in the 3′ untranslated region of transcripts …

Subcellular Distribution of Xenopus XEL-1 Protein, a Member of the Neuron-Specific ELAV/Hu Family, Revealed by Epitope Tagging

M Perron, P BOURLITIO, M Wegnez… - DNA and cell …, 1997 - liebertpub.com
Drosophila and vertebrate elav/Hu genes are involved in the development and the
maintenance of the nervous system. They all encode proteins that contain three RNA …