Proteomics is widely envisioned as playing a significant role in the translation of genomics to
clinically useful applications, especially in the areas of diagnostics and prognostics. In the …

The novel discipline of proteomics has experienced a rapid growth in the recent past and
has a great potential for the future. Involving several fields, it offers various advantages: The …

Abstract Treatment effectiveness for kidney disease is limited by lack of accuracy, sensitivity,
specificity of diagnostic, prognostic, and therapeutic biomarkers. The gold standard test …

Proteins are the functional output of genes. The proteome is defined as the expressed
protein and peptide complement of a cell, organ, or organism, including all isoforms and …

Proteomics-based approaches are generating considerable data in clinical nephrology
covering almost all aspects of the discipline. Proteomic experiments commonly involve …

Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …

Biomarkers have the potential to greatly facilitate diagnosis and treatment of patients with
various forms of kidney disease. State-of-the-art mass spectrometry-based methods possess …

Many challenges exist with disease-state biomarker identification. These challenges include
sample heterogeneity, poorly designed sample sets, insufficient numbers of samples, as …

Abstract Knowledge of the human genome has fertilized research in the embryonic field of
proteomics. The aim of this Review is to examine the recent application of emerging …

Introduction: Inter-individual variability in response to drug treatment has induced an
increased demand for decisions via personalize medicine. Also, the contribution of …